In situ generation of nucleophilic allenes by the gold-catalyzed rearrangement of propargylic esters for the highly diastereoselective formation of intermolecular C(sp3)-C(sp2) bonds
New perspectives, in particular for the synthesis of isochromane derivatives (see scheme), are provided by the title reaction. Excellent diastereoselectivites are achieved in this reaction which proceeds through a gold-catalyzed 1,3-acyloxy migration. In some cases exclusively the Z isomer is detect...
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| Autores principales: | , , , |
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| Formato: | Article (Journal) |
| Lenguaje: | inglés |
| Publicado: |
12 June 2013
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| In: |
Angewandte Chemie. International edition
Year: 2013, Volumen: 52, Número: 29, Pages: 7586-7589 |
| ISSN: | 1521-3773 |
| DOI: | 10.1002/anie.201302402 |
| Acceso en línea: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/anie.201302402 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201302402 
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| Notas de Autor: | Yang Yu, Weibo Yang, Frank Rominger, and A. Stephen K. Hashmi |
| Sumario: | New perspectives, in particular for the synthesis of isochromane derivatives (see scheme), are provided by the title reaction. Excellent diastereoselectivites are achieved in this reaction which proceeds through a gold-catalyzed 1,3-acyloxy migration. In some cases exclusively the Z isomer is detected. |
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| Notas: | Im Titel sind die Zahlen 3 und 2 hochgestellt Gesehen am 26.07.2021 |
| Descripción Física: | Online Resource |
| ISSN: | 1521-3773 |
| DOI: | 10.1002/anie.201302402 |