Endoreplication
Developmentally programmed polyploidy occurs by at least four different mechanisms, two of which (endoreduplication and endomitosis) involve switching from mitotic cell cycles to endocycles by the selective loss of mitotic cyclin-dependent kinase (CDK) activity and bypassing many of the processes of...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2013
|
| In: |
Cold Spring Harbor perspectives in biology
Year: 2013, Volume: 5, Issue: 1, Pages: 1-16 |
| ISSN: | 1943-0264 |
| DOI: | 10.1101/cshperspect.a012948 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1101/cshperspect.a012948 Verlag, lizenzpflichtig, Volltext: http://cshperspectives.cshlp.org/content/5/1/a012948 |
| Author Notes: | Norman Zielke, Bruce A. Edgar, and Melvin L. DePamphilis |
| Summary: | Developmentally programmed polyploidy occurs by at least four different mechanisms, two of which (endoreduplication and endomitosis) involve switching from mitotic cell cycles to endocycles by the selective loss of mitotic cyclin-dependent kinase (CDK) activity and bypassing many of the processes of mitosis. Here we review the mechanisms of endoreplication, focusing on recent results from Drosophila and mice. |
|---|---|
| Item Description: | Gesehen am 28.07.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1943-0264 |
| DOI: | 10.1101/cshperspect.a012948 |