Endoreplication

Developmentally programmed polyploidy occurs by at least four different mechanisms, two of which (endoreduplication and endomitosis) involve switching from mitotic cell cycles to endocycles by the selective loss of mitotic cyclin-dependent kinase (CDK) activity and bypassing many of the processes of...

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Bibliographic Details
Main Authors: Zielke, Norman (Author) , Edgar, Bruce (Author) , DePamphilis, Melvin L. (Author)
Format: Article (Journal)
Language:English
Published: 2013
In: Cold Spring Harbor perspectives in biology
Year: 2013, Volume: 5, Issue: 1, Pages: 1-16
ISSN:1943-0264
DOI:10.1101/cshperspect.a012948
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1101/cshperspect.a012948
Verlag, lizenzpflichtig, Volltext: http://cshperspectives.cshlp.org/content/5/1/a012948
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Author Notes:Norman Zielke, Bruce A. Edgar, and Melvin L. DePamphilis
Description
Summary:Developmentally programmed polyploidy occurs by at least four different mechanisms, two of which (endoreduplication and endomitosis) involve switching from mitotic cell cycles to endocycles by the selective loss of mitotic cyclin-dependent kinase (CDK) activity and bypassing many of the processes of mitosis. Here we review the mechanisms of endoreplication, focusing on recent results from Drosophila and mice.
Item Description:Gesehen am 28.07.2021
Physical Description:Online Resource
ISSN:1943-0264
DOI:10.1101/cshperspect.a012948