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“Include me if you can”: reasons for low enrollment of pediatric patients in a psychopharmacological trial

Low recruitment in clinical trials is a common and costly problem which undermines medical research. This study aimed to investigate the challenges faced in recruiting children and adolescents with obsessive-compulsive disorder and autism spectrum disorder for a randomized, double-blind, placebo-con...

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Main Authors: Niemeyer, Larissa (Author) , Mechler, Konstantin (Author) , Buitelaar, Jan (Author) , Durston, Sarah (Author) , Gooskens, Bram (Author) , Oranje, Bob (Author) , Banaschewski, Tobias (Author) , Dittmann, Ralf (Author) , Häge, Alexander (Author)
Format: Article (Journal)
Language:English
Published: 01 March 2021
In: Trials
Year: 2021, Volume: 22, Pages: 1-11
ISSN:1468-6694
DOI:10.1186/s13063-021-05119-6
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13063-021-05119-6
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Author Notes:Larissa Niemeyer, Konstantin Mechler, Jan Buitelaar, Sarah Durston, Bram Gooskens, Bob Oranje, Tobias Banaschewski, Ralf W. Dittmann and Alexander Häge
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Summary:Low recruitment in clinical trials is a common and costly problem which undermines medical research. This study aimed to investigate the challenges faced in recruiting children and adolescents with obsessive-compulsive disorder and autism spectrum disorder for a randomized, double-blind, placebo-controlled clinical trial and to analyze reasons for non-participation. The trial was part of the EU FP7 project TACTICS (Translational Adolescent and Childhood Therapeutic Interventions in Compulsive Syndromes).
Item Description:Gesehen am 30.07.2021
Physical Description:Online Resource
ISSN:1468-6694
DOI:10.1186/s13063-021-05119-6

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