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Analyzing non-sentinel axillary metastases in patients with T3-T4 cN0 early breast cancer and tumor-involved sentinel lymph nodes undergoing breast-conserving therapy or mastectomy

In the ACOSOG Z0011 trial, completing axillary lymph node dissection (cALND) did not benefit patients with T1-T2 cN0 early breast cancer and 1-2 positive sentinel lymph nodes (SLN) undergoing breast-conserving surgery (BCT). This paper reports cALND rates in the clinical routine for patients who had...

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Bibliographic Details
Main Authors: Riedel, Fabian (Author) , Heil, Jörg (Author) , Feißt, Manuel (Author) , Moderow, Mareike (Author) , Au, Alexandra von (Author) , Domschke, Christoph (Author) , Michel, Laura L. (Author) , Schäfgen, Benedikt (Author) , Golatta, Michael (Author) , Hennigs, André (Author)
Format: Article (Journal)
Language:English
Published: 20 August 2020
In: Breast cancer research and treatment
Year: 2020, Volume: 184, Issue: 2, Pages: 627-636
ISSN:1573-7217
DOI:10.1007/s10549-020-05876-z
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s10549-020-05876-z
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Author Notes:Fabian Riedel, Joerg Heil, Manuel Feisst, Mareike Moderow, Alexandra von Au, Christoph Domschke, Laura Michel, Benedikt Schaefgen, Michael Golatta, André Hennigs
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Summary:In the ACOSOG Z0011 trial, completing axillary lymph node dissection (cALND) did not benefit patients with T1-T2 cN0 early breast cancer and 1-2 positive sentinel lymph nodes (SLN) undergoing breast-conserving surgery (BCT). This paper reports cALND rates in the clinical routine for patients who had higher (T3-T4) tumor stages and/or underwent mastectomy but otherwise met the ACOSOG Z0011 eligibility criteria. Aim of this study is to determine cALND time trends and non-sentinel axillary metastases (NSAM) rates to estimate occult axillary tumor burden.
Item Description:Gesehen am 12.08.2021
Physical Description:Online Resource
ISSN:1573-7217
DOI:10.1007/s10549-020-05876-z

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