Analyzing non-sentinel axillary metastases in patients with T3-T4 cN0 early breast cancer and tumor-involved sentinel lymph nodes undergoing breast-conserving therapy or mastectomy
In the ACOSOG Z0011 trial, completing axillary lymph node dissection (cALND) did not benefit patients with T1-T2 cN0 early breast cancer and 1-2 positive sentinel lymph nodes (SLN) undergoing breast-conserving surgery (BCT). This paper reports cALND rates in the clinical routine for patients who had...
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| Hauptverfasser: | , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
20 August 2020
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| In: |
Breast cancer research and treatment
Year: 2020, Jahrgang: 184, Heft: 2, Pages: 627-636 |
| ISSN: | 1573-7217 |
| DOI: | 10.1007/s10549-020-05876-z |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s10549-020-05876-z
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| Verfasserangaben: | Fabian Riedel, Joerg Heil, Manuel Feisst, Mareike Moderow, Alexandra von Au, Christoph Domschke, Laura Michel, Benedikt Schaefgen, Michael Golatta, André Hennigs |
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| 520 | |a In the ACOSOG Z0011 trial, completing axillary lymph node dissection (cALND) did not benefit patients with T1-T2 cN0 early breast cancer and 1-2 positive sentinel lymph nodes (SLN) undergoing breast-conserving surgery (BCT). This paper reports cALND rates in the clinical routine for patients who had higher (T3-T4) tumor stages and/or underwent mastectomy but otherwise met the ACOSOG Z0011 eligibility criteria. Aim of this study is to determine cALND time trends and non-sentinel axillary metastases (NSAM) rates to estimate occult axillary tumor burden. | ||
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