The rationale behind implant coatings to promote osteointegration, bone healing or regeneration
Implant loosening, bone healing failure, implant-associated infections, and large bony defects remain challenges in orthopedic surgery. Implant surface modifications and coatings are being developed to promote osteointegration, prevent colonization by bacteria, and release bioactive factors. The fol...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2021
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| In: |
Injury
Year: 2021, Volume: 52, Pages: S106-S111 |
| ISSN: | 1879-0267 |
| DOI: | 10.1016/j.injury.2020.11.050 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.injury.2020.11.050 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S002013832030975X 
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| Author Notes: | Kai Borcherding, Gerhard Schmidmaier, Gunther O. Hofmann, Britt Wildemann |
| Summary: | Implant loosening, bone healing failure, implant-associated infections, and large bony defects remain challenges in orthopedic surgery. Implant surface modifications and coatings are being developed to promote osteointegration, prevent colonization by bacteria, and release bioactive factors. The following mini-review briefly discusses the clinical problem, explains the four “osteos”, presents examples of coatings used for different orthopedic indications, and finally raises awareness of the coating and translational requirements. |
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| Item Description: | Gesehen am 18.08.2021 First published: 21 November 2020 |
| Physical Description: | Online Resource |
| ISSN: | 1879-0267 |
| DOI: | 10.1016/j.injury.2020.11.050 |