The rationale behind implant coatings to promote osteointegration, bone healing or regeneration

Implant loosening, bone healing failure, implant-associated infections, and large bony defects remain challenges in orthopedic surgery. Implant surface modifications and coatings are being developed to promote osteointegration, prevent colonization by bacteria, and release bioactive factors. The fol...

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Hauptverfasser: Borcherding, Kai (VerfasserIn) , Schmidmaier, Gerhard (VerfasserIn) , Hofmann, Gunther O. (VerfasserIn) , Wildemann, Britt (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2021
In: Injury
Year: 2021, Jahrgang: 52, Pages: S106-S111
ISSN:1879-0267
DOI:10.1016/j.injury.2020.11.050
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.injury.2020.11.050
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S002013832030975X
Volltext
Verfasserangaben:Kai Borcherding, Gerhard Schmidmaier, Gunther O. Hofmann, Britt Wildemann
Beschreibung
Zusammenfassung:Implant loosening, bone healing failure, implant-associated infections, and large bony defects remain challenges in orthopedic surgery. Implant surface modifications and coatings are being developed to promote osteointegration, prevent colonization by bacteria, and release bioactive factors. The following mini-review briefly discusses the clinical problem, explains the four “osteos”, presents examples of coatings used for different orthopedic indications, and finally raises awareness of the coating and translational requirements.
Beschreibung:Gesehen am 18.08.2021
First published: 21 November 2020
Beschreibung:Online Resource
ISSN:1879-0267
DOI:10.1016/j.injury.2020.11.050