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Hydrocortisone dosing in children with classic congenital adrenal hyperplasia: results of the German/Austrian registry

Treatment of classic congenital adrenal hyperplasia (CAH) is necessary to compensate for glucocorticoid/mineralocorticoid deficiencies and to suppress androgen excess. Hydrocortisone (HC) is preferred in growing children with classic CAH but recommendations regarding dosage/administration are incons...

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Main Authors: Hoyer-Kuhn, Heike-Katharina (Author) , Huebner, Angela (Author) , Richter-Unruh, Annette (Author) , Bettendorf, Markus (Author) , Rohrer, Tilman (Author) , Kapelari, Klaus (Author) , Riedl, Stefan (Author) , Mohnike, Klaus (Author) , Dörr, Helmuth-Günther (Author) , Roehl, Friedrich-Wilhelm (Author) , Fink, Katharina (Author) , Holl, Reinhard W. (Author) , Wölfle, Joachim (Author)
Format: Article (Journal)
Language:English
Published: 28 April 2021
In: Endocrine Connections
Year: 2021, Volume: 10, Issue: 5, Pages: 561-569
ISSN:2049-3614
DOI:10.1530/EC-21-0023
Online Access:Resolving-System, kostenfrei: https://doi.org/10.1530/EC-21-0023
Verlag, lizenzpflichtig, Volltext: https://ec.bioscientifica.com/view/journals/ec/10/5/EC-21-0023.xml
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Author Notes:Heike Hoyer-Kuhn, Angela Huebner, Anette Richter-Unruh, Markus Bettendorf, Tilman Rohrer, Klaus Kapelari, Stefan Riedl, Klaus Mohnike, Helmuth-Günther Dörr, Friedrich-Wilhelm Roehl, Katharina Fink, Reinhard W. Holl, Joachim Woelfle
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Summary:Treatment of classic congenital adrenal hyperplasia (CAH) is necessary to compensate for glucocorticoid/mineralocorticoid deficiencies and to suppress androgen excess. Hydrocortisone (HC) is preferred in growing children with classic CAH but recommendations regarding dosage/administration are inconsistent. The aim of this study was to evaluate HC dosing in children with CAH in relation to chronological age, sex, and phenotype based on a multicenter CAH registry.
Item Description:Accepted manuscript published online 28 April 2021
Gesehen am 23.08.2021
Physical Description:Online Resource
ISSN:2049-3614
DOI:10.1530/EC-21-0023

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