In vitro maturation of immature oocytes from ovarian tissue prior to shipment to a cryobank

Female fertility preservation prior to gonadotoxic therapies can be achieved by the cryopreservation of ovarian cortical tissue. Immature oocytes may be recovered during the preparation, matured in vitro and lead to live births, thereby providing an additional option for fertility preservation. The...

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Main Authors: Dietrich, Jens Erik (Author) , Jauckus, Julia (Author) , Hoffmann, Sabrina (Author) , Liebenthron, Jana (Author) , Capp, Edison (Author) , Strowitzki, Thomas (Author) , Germeyer, Ariane (Author)
Format: Article (Journal)
Language:English
Published: 17 June 2020
In: Archives of gynecology and obstetrics
Year: 2020, Volume: 302, Issue: 4, Pages: 1019-1024
ISSN:1432-0711
DOI:10.1007/s00404-020-05643-x
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00404-020-05643-x
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Author Notes:Jens Erik Dietrich, Julia Jauckus, Sabrina Hoffmann, Jana Liebenthron, Edison Capp, Thomas Strowitzki, Ariane Germeyer
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Summary:Female fertility preservation prior to gonadotoxic therapies can be achieved by the cryopreservation of ovarian cortical tissue. Immature oocytes may be recovered during the preparation, matured in vitro and lead to live births, thereby providing an additional option for fertility preservation. The purpose of this study was to test the feasibility of this approach in a setting with unilateral biopsy of a small piece of ovarian tissue and minimal tissue preparation prior to shipment to an external cryobank.
Item Description:Gesehen am 08.09.2021
Physical Description:Online Resource
ISSN:1432-0711
DOI:10.1007/s00404-020-05643-x