Illuminating Plasmodium invasion by lattice-light-sheet microscopy
Plasmodium merozoites invade erythrocytes in a stepwise manner through ligand binding, calcium signaling, and membrane deformation. Using a recently developed light-sheet microscope, Geoghegan et al. investigated invasion with unprecedented temporal resolution. Their spectacular footage revealed rol...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
September 2021
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| In: |
Trends in parasitology
Year: 2021, Volume: 37, Issue: 9, Pages: 777-779 |
| ISSN: | 1471-5007 |
| DOI: | 10.1016/j.pt.2021.07.008 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.pt.2021.07.008 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1471492221001732 
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| Author Notes: | Markus Ganter and Friedrich Frischknecht |
| Summary: | Plasmodium merozoites invade erythrocytes in a stepwise manner through ligand binding, calcium signaling, and membrane deformation. Using a recently developed light-sheet microscope, Geoghegan et al. investigated invasion with unprecedented temporal resolution. Their spectacular footage revealed roles for host cell cholesterol and pore formation at the parasite-host cell interface. |
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| Item Description: | Gesehen am 05.10.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1471-5007 |
| DOI: | 10.1016/j.pt.2021.07.008 |