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Cardiovascular effects of (R)- and (S)-verapamil and racemic verapamil in humans: a placebo-controlled study

To characterise the comparative potency of optically pure (R)- and (S)-verapamil as regards negative dromotropic effects on atrioventricular (AV) node conduction and to compare the hemodynamic effects of single doses of the enantiomers in healthy volunteers.

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Bibliographic Details
Main Authors: Busse, Dagmar (Author) , Templin, Silke (Author) , Mikus, Gerd (Author) , Schwab, Matthias (Author) , Hofmann, Ute (Author) , Eichelbaum, Michel (Author) , Kivistö, Kari T. (Author)
Format: Article (Journal)
Language:English
Published: 4 July 2006
In: European journal of clinical pharmacology
Year: 2006, Volume: 62, Issue: 8, Pages: 613-619
ISSN:1432-1041
DOI:10.1007/s00228-006-0154-7
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00228-006-0154-7
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007%2Fs00228-006-0154-7
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Author Notes:Dagmar Busse, Silke Templin, Gerd Mikus, Matthias Schwab, Ute Hofmann, Michel Eichelbaum, Kari T. Kivistö
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Summary:To characterise the comparative potency of optically pure (R)- and (S)-verapamil as regards negative dromotropic effects on atrioventricular (AV) node conduction and to compare the hemodynamic effects of single doses of the enantiomers in healthy volunteers.
Item Description:Gesehen am 07.10.2021
Physical Description:Online Resource
ISSN:1432-1041
DOI:10.1007/s00228-006-0154-7

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