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Kidney re-transplantation in a child across the barrier of persisting angiotensin II type I receptor antibodies

Approximately 20% of antibody-mediated rejection (ABMR) episodes in the absence of donor-specific antibodies against human leucocyte antigens (HLA-DSA) in pediatric and adult kidney transplant recipients are associated with, and presumably caused by, antibodies against the angiotensin type 1 recepto...

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Bibliographic Details
Main Authors: Gold, Annika (Author) , Fichtner, Alexander (Author) , Choukair, Daniela (Author) , Schmitt, Claus P. (Author) , Süsal, Caner (Author) , Dragun, Duska (Author) , Tönshoff, Burkhard (Author)
Format: Article (Journal)
Language:English
Published: 2021
In: Pediatric nephrology
Year: 2021, Volume: 36, Issue: 3, Pages: 725-729
ISSN:1432-198X
DOI:10.1007/s00467-020-04879-8
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00467-020-04879-8
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Author Notes:Annika Gold, Alexander Fichtner, Daniela Choukair, Claus Peter Schmitt, Caner Süsal, Duska Dragun, Burkhard Tönshoff
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Summary:Approximately 20% of antibody-mediated rejection (ABMR) episodes in the absence of donor-specific antibodies against human leucocyte antigens (HLA-DSA) in pediatric and adult kidney transplant recipients are associated with, and presumably caused by, antibodies against the angiotensin type 1 receptor (AT1R-Ab). While the role of AT1R-Ab for ABMR and graft failure is increasingly recognized, there is little information available on the management of these patients for re-transplantation over the barrier of persisting AT1R-Ab.
Item Description:Published online: 23 December 2020
Gesehen am 07.10.2021
Physical Description:Online Resource
ISSN:1432-198X
DOI:10.1007/s00467-020-04879-8

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