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Scaling of embryonic patterning based on phase-gradient encoding

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An ex vivo primary culture assay is developed that recapitulates mouse embryonic mesodermal patterning and segment formation; using this approach, it is shown that oscillating gene activity is central to maintain stable proportions during development.

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Bibliographic Details
Main Authors: Lauschke, Volker Martin (Author) , Tsiairis, Charisios D. (Author) , François, Paul (Author) , Aulehla, Alexander (Author)
Format: Article (Journal)
Language:English
Published: 2013
In: Nature
Year: 2013, Volume: 493, Issue: 7430, Pages: 101-105
ISSN:1476-4687
DOI:10.1038/nature11804
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nature11804
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nature11804
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Author Notes:Volker M. Lauschke, Charisios D. Tsiairis, Paul François & Alexander Aulehla
Description
Summary:An ex vivo primary culture assay is developed that recapitulates mouse embryonic mesodermal patterning and segment formation; using this approach, it is shown that oscillating gene activity is central to maintain stable proportions during development.
Item Description:Published online 19 December 2012
Gesehen am 14.10.2021
Physical Description:Online Resource
ISSN:1476-4687
DOI:10.1038/nature11804

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