Selective Janus kinase inhibition preserves interferon-λ-mediated antiviral responses

TYK2 is required for efficient IFN-α/β signaling but dispensable for IFN-λ-mediated antiviral protection in epithelial cells.

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Bibliographic Details
Main Authors:	Schnepf, Daniel (Author) , Crotta, Stefania (Author) , Thamamongood, Thiprampai (Author) , Stanifer, Megan (Author) , Polcik, Laura (Author) , Ohnemus, Annette (Author) , Vier, Juliane (Author) , Jakob, Celia (Author) , Llorian, Miriam (Author) , Gad, Hans Henrik (Author) , Hartmann, Rune (Author) , Strobl, Birgit (Author) , Kirschnek, Susanne (Author) , Boulant, Steeve (Author) , Schwemmle, Martin (Author) , Wack, Andreas (Author) , Staeheli, Peter (Author)
Format:	Article (Journal)
Language:	English
Published:	14 May 2021
In:	Science immunology Year: 2021, Volume: 6, Issue: 59, Pages: 1-13
ISSN:	2470-9468
Online Access:	Verlag, lizenzpflichtig, Volltext: https://www.science.org/doi/abs/10.1126/sciimmunol.abd5318
Author Notes:	Daniel Schnepf, Stefania Crotta, Thiprampai Thamamongood, Megan Stanifer, Laura Polcik, Annette Ohnemus, Juliane Vier, Celia Jakob, Miriam Llorian, Hans Henrik Gad, Rune Hartmann, Birgit Strobl, Susanne Kirschnek, Steeve Boulant, Martin Schwemmle, Andreas Wack, Peter Staeheli

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Summary:	TYK2 is required for efficient IFN-α/β signaling but dispensable for IFN-λ-mediated antiviral protection in epithelial cells.
Item Description:	Gesehen am 14.10.2021
Physical Description:	Online Resource
ISSN:	2470-9468