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Non-invasive fractional flow reserve (FFRCT) in the evaluation of acute chest pain: concepts and first experiences

Objective - To evaluate 30 day rate of major adverse cardiac events (MACE) utilizing cCTA and FFRCT for evaluation of patients presenting to the Emergency Department (ED) with acute chest pain. - Materials and methods - Patients between the ages of 18-95 years who underwent clinically indicated cCTA...

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Main Authors: Fischer, Andreas (Author) , van Assen, Marly (Author) , Schoepf, U. Joseph (Author) , Matuskowitz, Andrew J. (Author) , Varga-Szemes, Akos (Author) , Golden, Joseph W. (Author) , Giovagnoli, Dante A. (Author) , Tesche, Christian (Author) , Bayer, Richard R. (Author)
Format: Article (Journal)
Language:English
Published: May 2021
In: European journal of radiology
Year: 2021, Volume: 138, Pages: 1-6
ISSN:1872-7727
DOI:10.1016/j.ejrad.2021.109633
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ejrad.2021.109633
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0720048X21001133
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Author Notes:Andreas M. Fischer, Marly van Assen, U. Joseph Schoepf, Andrew J. Matuskowitz, Akos Varga-Szemes, Joseph W. Golden, Dante A. Giovagnoli, Christian Tesche, Richard R. Bayer II
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Summary:Objective - To evaluate 30 day rate of major adverse cardiac events (MACE) utilizing cCTA and FFRCT for evaluation of patients presenting to the Emergency Department (ED) with acute chest pain. - Materials and methods - Patients between the ages of 18-95 years who underwent clinically indicated cCTA and FFRCT in the evaluation of acute chest pain in the emergency department were retrospectively evaluated for 30 day MACE, repeat presentation/admission for chest pain, revascularization, and additional testing. - Results - A total of 59 patients underwent CCTA and subsequent FFRCT for the evaluation of acute chest pain in the ED over the enrollment period. 32 out of 59 patients (54 %) had negative FFRCT (>0.80) out of whom 18 patients (55 %) were discharged from the ED. Out of the 32 patients without functionally significant CAD by FFRCT, 32 patients (100 %) underwent no revascularization and 32 patients (100 %) had no MACE at the 30-day follow-up period. - Conclusion - In this limited retrospective study, patients presenting to the ED with acute chest pain and with CCTA with subsequent FFRCT of >0.8 had no MACE at 30 days; however, for many of these patients results were not available at time of clinical decision making by the ED physician.
Item Description:Im Text ist "CT" tiefgestellt
Gesehen am 20.10.2021
Physical Description:Online Resource
ISSN:1872-7727
DOI:10.1016/j.ejrad.2021.109633

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