Pirfenidone vs. nintedanib in patients with idiopathic pulmonary fibrosis: a retrospective cohort study

Idiopathic pulmonary fibrosis, mortality, hospitalization, health care costs, administrative data, drugs, statutory health insurance

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Bibliographic Details
Main Authors: Marijic, Pavo (Author) , Schwarzkopf, Larissa (Author) , Schwettmann, Lars (Author) , Ruhnke, Thomas (Author) , Trudzinski, Franziska (Author) , Kreuter, Michael (Author)
Format: Article (Journal)
Language:English
Published: 19 October 2021
In: Respiratory research
Year: 2021, Volume: 22, Pages: 1-11
ISSN:1465-993X
DOI:10.1186/s12931-021-01857-y
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12931-021-01857-y
Resolving-System, kostenfrei: https://doi.org/10.1186/s12931-021-01857-y
Resolving-System, kostenfrei: https://doi.org/10.25673/110784
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Author Notes:Pavo Marijic, Larissa Schwarzkopf, Lars Schwettmann, Thomas Ruhnke, Franziska Trudzinski and Michael Kreuter
Description
Summary:Idiopathic pulmonary fibrosis, mortality, hospitalization, health care costs, administrative data, drugs, statutory health insurance
Two antifibrotic drugs, pirfenidone and nintedanib, are licensed for the treatment of patients with idiopathic pulmonary fibrosis (IPF). However, there is neither evidence from prospective data nor a guideline recommendation, which drug should be preferred over the other. This study aimed to compare pirfenidone and nintedanib-treated patients regarding all-cause mortality, all-cause and respiratory-related hospitalizations, and overall as well as respiratory-related health care costs borne by the Statutory Health Insurance (SHI).
Item Description:Gesehen am 30.12.2021
Physical Description:Online Resource
ISSN:1465-993X
DOI:10.1186/s12931-021-01857-y