Id1 and Id3 are regulated through matrix-assisted autocrine BMP signaling and represent therapeutic targets in melanoma
New treatment strategies for melanoma are urgently needed. This study shows that the extracellular matrix can stimulate autocrine bone morphogenetic protein signaling in melanoma cells, leading to up...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2021
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| In: |
Advanced therapeutics
Year: 2021, Jahrgang: 4, Heft: 2, Pages: 1-17 |
| ISSN: | 2366-3987 |
| DOI: | 10.1002/adtp.202000065 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1002/adtp.202000065 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/adtp.202000065 |
| Verfasserangaben: | Georg Sedlmeier, Vanessa Al-Rawi, Justyna Buchert, Klaus Yserentant, Melanie Rothley, Anastasia Steshina, Simone Gräßle, Ruo-Lin Wu, Thomas Hurrle, Wilfrid Richer, Charles Decraene, Wilko Thiele, Jochen Utikal, Wasim Abuillan, Motomu Tanaka, Dirk-Peter Herten, Caroline S. Hill, Boyan K. Garvalov, Nicole Jung, Stefan Bräse, and Jonathan P. Sleeman |
| Zusammenfassung: | New treatment strategies for melanoma are urgently needed. This study shows that the extracellular matrix can stimulate autocrine bone morphogenetic protein signaling in melanoma cells, leading to up... |
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| Beschreibung: | First published: 12 October 2020 Gesehen am 26.10.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 2366-3987 |
| DOI: | 10.1002/adtp.202000065 |