Aβ misfolding in blood plasma is inversely associated with body mass index even in middle adulthood

To understand the potential for early intervention and prevention measures in Alzheimer’s disease, the association between risk factors and early pathological change needs to be assessed. Hence, the aim of this study was to determine whether risk factors of Alzheimer’s clinical syndrome (clinical AD...

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Main Authors: Möllers, Tobias (Author) , Stocker, Hannah (Author) , Perna, Laura (Author) , Nabers, Andreas (Author) , Rujescu, Dan (Author) , Hartmann, Annette M. (Author) , Holleczek, Bernd (Author) , Schöttker, Ben (Author) , Gerwert, Klaus (Author) , Brenner, Hermann (Author)
Format: Article (Journal)
Language:English
Published: 30 August 2021
In: Alzheimer's research & therapy
Year: 2021, Volume: 13, Issue: 1, Pages: 1-9
ISSN:1758-9193
DOI:10.1186/s13195-021-00889-2
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Author Notes:Tobias Möllers, Hannah Stocker, Laura Perna, Andreas Nabers, Dan Rujescu, Annette M. Hartmann, Bernd Holleczek, Ben Schöttker, Klaus Gerwert and Hermann Brenner
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Summary:To understand the potential for early intervention and prevention measures in Alzheimer’s disease, the association between risk factors and early pathological change needs to be assessed. Hence, the aim of this study was to determine whether risk factors of Alzheimer’s clinical syndrome (clinical AD), such as body mass index (BMI), are associated with Aβ misfolding in blood, a strong risk marker for AD among older adults.
Item Description:Gesehen am 08.11.2021
Physical Description:Online Resource
ISSN:1758-9193
DOI:10.1186/s13195-021-00889-2