Cover Image

Advanced glycated end-products (AGE) during haemodialysis treatment: discrepant results with different methodologies reflecting the heterogeneity of AGE compounds

There has been much recent interest in accumulation of advanced glycation end-products (AGE) in uraemic patients. Analysis of AGE has been difficult, because commonly used methodologies, i.e. immunodetection assays or fluorescence measurements, reflect group reactivity and are not specific for chemi...

Full description

Saved in:
Bibliographic Details
Main Authors: Henle, Thomas (Author) , Deppisch, Reinhold (Author) , Beck, Werner (Author) , Hergesell, Olaf (Author) , Hänsch, Gertrud Maria (Author) , Ritz, Eberhard (Author)
Format: Article (Journal)
Language:English
Published: 01 August 1999
In: Nephrology, dialysis, transplantation
Year: 1999, Volume: 14, Issue: 8, Pages: 1968-1975
ISSN:1460-2385
DOI:10.1093/ndt/14.8.1968
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/ndt/14.8.1968
Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/ndt/article/14/8/1968/1808532
Get full text
Author Notes:Thomas Henle, Reinhold Deppisch, Werner Beck, Olaf Hergesell, Gertrud M. Hänsch and Eberhard Ritz
Description
Summary:There has been much recent interest in accumulation of advanced glycation end-products (AGE) in uraemic patients. Analysis of AGE has been difficult, because commonly used methodologies, i.e. immunodetection assays or fluorescence measurements, reflect group reactivity and are not specific for chemically defined substances. Some investigators measured individual AGE compounds, e.g. pentosidine, carboxymethyllysine, pyrraline or imidazolone, but a systematic assessment of known compounds using specific HPLC methods in diabetic and non-diabetic end-stage renal disease (ESRD) patients during treatment has not been performed.
Item Description:Gesehen am 11.11.2021
Physical Description:Online Resource
ISSN:1460-2385
DOI:10.1093/ndt/14.8.1968

Similar Items