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Differences between auto-fluorescence and tetracycline-fluorescence in medication-related osteonecrosis of the jaw: a preclinical proof of concept study in the mini-pig

Fluorescence-guided bone surgery is a well-established technique in the treatment of medication-related osteonecrosis of the jaw. No histopathological evidence for bone auto-fluorescence is currently available, and thus, any differences from tetracycline-fluorescence remain unclear. Therefore, the g...

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Main Authors: Ristow, Oliver (Author) , Nehrbaß, Dirk (Author) , Zeiter, Stephan (Author) , Arens, Daniel (Author) , Moratin, Julius (Author) , Pautke, Christoph (Author) , Hoffmann, Jürgen (Author) , Freudlsperger, Christian (Author) , Otto, Sven (Author)
Format: Article (Journal)
Language:English
Published: 22 May 2020
In: Clinical oral investigations
Year: 2020, Volume: 24, Issue: 12, Pages: 4625-4637
ISSN:1436-3771
DOI:10.1007/s00784-020-03332-2
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00784-020-03332-2
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Author Notes:Oliver Ristow, Dirk Nehrbass, Stephan Zeiter, Daniel Arens, Julius Moratin, Christoph Pautke, Jürgen Hoffmann, Christian Freudlsperger, Sven Otto
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Summary:Fluorescence-guided bone surgery is a well-established technique in the treatment of medication-related osteonecrosis of the jaw. No histopathological evidence for bone auto-fluorescence is currently available, and thus, any differences from tetracycline-fluorescence remain unclear. Therefore, the goals of this study were to find out if macroscopic and histological differences occur between the auto- and tetracycline-fluorescence in the delineation of viable and necrotic jawbone in the mini-pig.
Item Description:Gesehen am 18.11.2021
Physical Description:Online Resource
ISSN:1436-3771
DOI:10.1007/s00784-020-03332-2

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