T-cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas
Gliomas are intrinsic brain tumors with a high degree of constitutive and acquired resistance to standard therapeutic modalities such as radiotherapy and alkylating chemotherapy. Glioma subtypes are recognized by characteristic mutations. Some of these characteristic mutations have shown to generate...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
15 January 2022
|
| In: |
Clinical cancer research
Year: 2022, Jahrgang: 28, Heft: 2, Pages: 378-389 |
| ISSN: | 1557-3265 |
| DOI: | 10.1158/1078-0432.CCR-21-1881 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1158/1078-0432.CCR-21-1881 Verlag, lizenzpflichtig, Volltext: https://clincancerres.aacrjournals.org/content/early/2021/11/01/1078-0432.CCR-21-1881 
|
| Verfasserangaben: | Michael Kilian, Mirco Friedrich, Khwab Sanghvi, Edward Green, Stefan Pusch, Daisuke Kawauchi, Martin Löwer, Jana K. Sonner, Christopher Krämer, Julia Zaman, Stefanie Jung, Michael O. Breckwoldt, Gerald Willimksy, Stefan B. Eichmüller, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten, and Lukas Bunse |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1778014798 | ||
| 003 | DE-627 | ||
| 005 | 20230126133521.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 211119s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1158/1078-0432.CCR-21-1881 |2 doi | |
| 035 | |a (DE-627)1778014798 | ||
| 035 | |a (DE-599)KXP1778014798 | ||
| 035 | |a (OCoLC)1341430872 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Kilian, Michael |d 1990- |e VerfasserIn |0 (DE-588)1220319422 |0 (DE-627)1736693255 |4 aut | |
| 245 | 1 | 0 | |a T-cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas |c Michael Kilian, Mirco Friedrich, Khwab Sanghvi, Edward Green, Stefan Pusch, Daisuke Kawauchi, Martin Löwer, Jana K. Sonner, Christopher Krämer, Julia Zaman, Stefanie Jung, Michael O. Breckwoldt, Gerald Willimksy, Stefan B. Eichmüller, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten, and Lukas Bunse |
| 264 | 1 | |c 15 January 2022 | |
| 300 | |a 12 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Published first November 15, 2021 | ||
| 500 | |a Gesehen am 20.01.2022 | ||
| 520 | |a Gliomas are intrinsic brain tumors with a high degree of constitutive and acquired resistance to standard therapeutic modalities such as radiotherapy and alkylating chemotherapy. Glioma subtypes are recognized by characteristic mutations. Some of these characteristic mutations have shown to generate immunogenic neoepitopes suitable for targeted immunotherapy. | ||
| 700 | 1 | |a Friedrich, Mirco |e VerfasserIn |0 (DE-588)1126663794 |0 (DE-627)881255246 |0 (DE-576)484646923 |4 aut | |
| 700 | 1 | |a Sanghvi, Khwab |d 1990- |e VerfasserIn |0 (DE-588)1201828864 |0 (DE-627)1685962580 |4 aut | |
| 700 | 1 | |a Green, Edward |e VerfasserIn |4 aut | |
| 700 | 1 | |a Pusch, Stefan |d 1979- |e VerfasserIn |0 (DE-588)137014155 |0 (DE-627)58945224X |0 (DE-576)30150623X |4 aut | |
| 700 | 1 | |a Kawauchi, Daisuke |e VerfasserIn |0 (DE-588)1163560944 |0 (DE-627)1027881920 |0 (DE-576)508052009 |4 aut | |
| 700 | 1 | |a Löwer, Martin |e VerfasserIn |4 aut | |
| 700 | 1 | |a Sonner, Jana K. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Krämer, Christopher |d 1997- |e VerfasserIn |0 (DE-588)1279191635 |0 (DE-627)1832479978 |4 aut | |
| 700 | 1 | |a Zaman, Julia |d 1992- |e VerfasserIn |0 (DE-588)1252767080 |0 (DE-627)1794403310 |4 aut | |
| 700 | 1 | |a Jung, Stefanie |e VerfasserIn |4 aut | |
| 700 | 1 | |a Breckwoldt, Michael O. |d 1983- |e VerfasserIn |0 (DE-588)1022496298 |0 (DE-627)716993392 |0 (DE-576)365498297 |4 aut | |
| 700 | 1 | |a Willimksy, Gerald |e VerfasserIn |4 aut | |
| 700 | 1 | |a Eichmüller, Stefan B. |d 1960- |e VerfasserIn |0 (DE-588)1025289226 |0 (DE-627)721986951 |0 (DE-576)37016704X |4 aut | |
| 700 | 1 | |a Deimling, Andreas von |d 1959- |e VerfasserIn |0 (DE-588)103034115X |0 (DE-627)735093946 |0 (DE-576)378138065 |4 aut | |
| 700 | 1 | |a Wick, Wolfgang |d 1970- |e VerfasserIn |0 (DE-588)120297736 |0 (DE-627)080586929 |0 (DE-576)186221320 |4 aut | |
| 700 | 1 | |a Sahm, Felix |d 1984- |e VerfasserIn |0 (DE-588)1022852132 |0 (DE-627)717318478 |0 (DE-576)366075020 |4 aut | |
| 700 | 1 | |a Platten, Michael |d 1971- |e VerfasserIn |0 (DE-588)121627780 |0 (DE-627)081431848 |0 (DE-576)261969811 |4 aut | |
| 700 | 1 | |a Bunse, Lukas |d 1988- |e VerfasserIn |0 (DE-588)1051941229 |0 (DE-627)787187399 |0 (DE-576)407600426 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Clinical cancer research |d Philadelphia, Pa. [u.a.] : AACR, 1995 |g 28(2022), 2 vom: Jan., Seite 378-389 |h Online-Ressource |w (DE-627)325489971 |w (DE-600)2036787-9 |w (DE-576)094502234 |x 1557-3265 |7 nnas |a T-cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas |
| 773 | 1 | 8 | |g volume:28 |g year:2022 |g number:2 |g month:01 |g pages:378-389 |g extent:12 |a T-cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas |
| 856 | 4 | 0 | |u https://doi.org/10.1158/1078-0432.CCR-21-1881 |x Resolving-System |x Verlag |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://clincancerres.aacrjournals.org/content/early/2021/11/01/1078-0432.CCR-21-1881 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20211119 | ||
| 993 | |a Article | ||
| 994 | |a 2022 | ||
| 998 | |g 1051941229 |a Bunse, Lukas |m 1051941229:Bunse, Lukas |d 60000 |d 62700 |e 60000PB1051941229 |e 62700PB1051941229 |k 0/60000/ |k 1/60000/62700/ |p 19 |y j | ||
| 998 | |g 121627780 |a Platten, Michael |m 121627780:Platten, Michael |d 60000 |d 62700 |e 60000PP121627780 |e 62700PP121627780 |k 0/60000/ |k 1/60000/62700/ |p 18 | ||
| 998 | |g 1022852132 |a Sahm, Felix |m 1022852132:Sahm, Felix |d 910000 |d 912000 |e 910000PS1022852132 |e 912000PS1022852132 |k 0/910000/ |k 1/910000/912000/ |p 17 | ||
| 998 | |g 120297736 |a Wick, Wolfgang |m 120297736:Wick, Wolfgang |d 910000 |d 911100 |e 910000PW120297736 |e 911100PW120297736 |k 0/910000/ |k 1/910000/911100/ |p 16 | ||
| 998 | |g 103034115X |a Deimling, Andreas von |m 103034115X:Deimling, Andreas von |d 910000 |d 912000 |e 910000PD103034115X |e 912000PD103034115X |k 0/910000/ |k 1/910000/912000/ |p 15 | ||
| 998 | |g 1025289226 |a Eichmüller, Stefan B. |m 1025289226:Eichmüller, Stefan B. |d 140000 |d 60000 |e 140000PE1025289226 |e 60000PE1025289226 |k 0/140000/ |k 0/60000/ |p 14 | ||
| 998 | |g 1022496298 |a Breckwoldt, Michael O. |m 1022496298:Breckwoldt, Michael O. |d 910000 |d 911100 |d 50000 |e 910000PB1022496298 |e 911100PB1022496298 |e 50000PB1022496298 |k 0/910000/ |k 1/910000/911100/ |k 0/50000/ |p 12 | ||
| 998 | |g 1252767080 |a Zaman, Julia |m 1252767080:Zaman, Julia |d 140000 |e 140000PZ1252767080 |k 0/140000/ |p 10 | ||
| 998 | |g 1279191635 |a Krämer, Christopher |m 1279191635:Krämer, Christopher |d 50000 |d 53100 |e 50000PK1279191635 |e 53100PK1279191635 |k 0/50000/ |k 1/50000/53100/ |p 9 | ||
| 998 | |g 1163560944 |a Kawauchi, Daisuke |m 1163560944:Kawauchi, Daisuke |d 50000 |e 50000PK1163560944 |k 0/50000/ |p 6 | ||
| 998 | |g 137014155 |a Pusch, Stefan |m 137014155:Pusch, Stefan |d 910000 |d 912000 |d 50000 |e 910000PP137014155 |e 912000PP137014155 |e 50000PP137014155 |k 0/910000/ |k 1/910000/912000/ |k 0/50000/ |p 5 | ||
| 998 | |g 1201828864 |a Sanghvi, Khwab |m 1201828864:Sanghvi, Khwab |d 60000 |d 62700 |e 60000PS1201828864 |e 62700PS1201828864 |k 0/60000/ |k 1/60000/62700/ |p 3 | ||
| 998 | |g 1126663794 |a Friedrich, Mirco |m 1126663794:Friedrich, Mirco |d 910000 |d 910100 |e 910000PF1126663794 |e 910100PF1126663794 |k 0/910000/ |k 1/910000/910100/ |p 2 | ||
| 998 | |g 1220319422 |a Kilian, Michael |m 1220319422:Kilian, Michael |d 60000 |d 62700 |e 60000PK1220319422 |e 62700PK1220319422 |k 0/60000/ |k 1/60000/62700/ |p 1 |x j | ||
| 999 | |a KXP-PPN1778014798 |e 4003671961 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["Michael Kilian, Mirco Friedrich, Khwab Sanghvi, Edward Green, Stefan Pusch, Daisuke Kawauchi, Martin Löwer, Jana K. Sonner, Christopher Krämer, Julia Zaman, Stefanie Jung, Michael O. Breckwoldt, Gerald Willimksy, Stefan B. Eichmüller, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten, and Lukas Bunse"]},"id":{"eki":["1778014798"],"doi":["10.1158/1078-0432.CCR-21-1881"]},"origin":[{"dateIssuedDisp":"15 January 2022","dateIssuedKey":"2022"}],"relHost":[{"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Gesehen am 08.06.2023","Fortsetzung der Druck-Ausgabe"],"title":[{"title_sort":"Clinical cancer research","title":"Clinical cancer research"}],"origin":[{"dateIssuedDisp":"1995-","dateIssuedKey":"1995","publisherPlace":"Philadelphia, Pa. [u.a.]","publisher":"AACR"}],"disp":"T-cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomasClinical cancer research","physDesc":[{"extent":"Online-Ressource"}],"recId":"325489971","id":{"issn":["1557-3265"],"eki":["325489971"],"zdb":["2036787-9"]},"part":{"year":"2022","volume":"28","pages":"378-389","issue":"2","extent":"12","text":"28(2022), 2 vom: Jan., Seite 378-389"},"corporate":[{"role":"isb","display":"American Association for Cancer Research"}],"name":{"displayForm":["American Association for Cancer Research"]},"pubHistory":["1.1995 -"]}],"person":[{"display":"Kilian, Michael","role":"aut","given":"Michael","family":"Kilian"},{"display":"Friedrich, Mirco","given":"Mirco","role":"aut","family":"Friedrich"},{"display":"Sanghvi, Khwab","given":"Khwab","role":"aut","family":"Sanghvi"},{"display":"Green, Edward","role":"aut","given":"Edward","family":"Green"},{"display":"Pusch, Stefan","given":"Stefan","role":"aut","family":"Pusch"},{"family":"Kawauchi","role":"aut","given":"Daisuke","display":"Kawauchi, Daisuke"},{"family":"Löwer","given":"Martin","role":"aut","display":"Löwer, Martin"},{"display":"Sonner, Jana K.","family":"Sonner","given":"Jana K.","role":"aut"},{"display":"Krämer, Christopher","family":"Krämer","role":"aut","given":"Christopher"},{"family":"Zaman","role":"aut","given":"Julia","display":"Zaman, Julia"},{"display":"Jung, Stefanie","role":"aut","given":"Stefanie","family":"Jung"},{"display":"Breckwoldt, Michael O.","role":"aut","given":"Michael O.","family":"Breckwoldt"},{"given":"Gerald","role":"aut","family":"Willimksy","display":"Willimksy, Gerald"},{"display":"Eichmüller, Stefan B.","role":"aut","given":"Stefan B.","family":"Eichmüller"},{"given":"Andreas von","role":"aut","family":"Deimling","display":"Deimling, Andreas von"},{"display":"Wick, Wolfgang","family":"Wick","role":"aut","given":"Wolfgang"},{"display":"Sahm, Felix","role":"aut","given":"Felix","family":"Sahm"},{"role":"aut","given":"Michael","family":"Platten","display":"Platten, Michael"},{"display":"Bunse, Lukas","family":"Bunse","given":"Lukas","role":"aut"}],"title":[{"title":"T-cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas","title_sort":"T-cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"language":["eng"],"note":["Published first November 15, 2021","Gesehen am 20.01.2022"],"recId":"1778014798","physDesc":[{"extent":"12 S."}]} | ||
| SRT | |a KILIANMICHTCELLRECEP1520 | ||