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Glucosamine protects against neuronal but not vascular damage in experimental diabetic retinopathy

Glucosamine, an intermetabolite of the hexosamine biosynthesis pathway (HBP), is a widely used nutritional supplement in osteoarthritis patients, a subset of whom also suffer from diabetes. HBP is activated in diabetic retinopathy (DR). The aim of this study is to investigate the yet unclear effects...

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Main Authors: Eshwaran, Rachana (Author) , Kolibabka, Matthias (Author) , Poschet, Gernot (Author) , Jainta, Gregor (Author) , Zhao, Di (Author) , Teuma, Loic (Author) , Murillo, Katharina (Author) , Hammes, Hans-Peter (Author) , Schmidt, Martina (Author) , Wieland, Thomas (Author) , Feng, Yuxi (Author)
Format: Article (Journal)
Language:English
Published: 8 September 2021
In: Molecular metabolism
Year: 2021, Volume: 54, Pages: 1-13
ISSN:2212-8778
DOI:10.1016/j.molmet.2021.101333
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.molmet.2021.101333
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S2212877821001800
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Author Notes:Rachana Eshwaran, Matthias Kolibabka, Gernot Poschet, Gregor Jainta, Di Zhao, Loic Teuma, Katharina Murillo, Hans-Peter Hammes, Martina Schmidt, Thomas Wieland, Yuxi Feng
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Summary:Glucosamine, an intermetabolite of the hexosamine biosynthesis pathway (HBP), is a widely used nutritional supplement in osteoarthritis patients, a subset of whom also suffer from diabetes. HBP is activated in diabetic retinopathy (DR). The aim of this study is to investigate the yet unclear effects of glucosamine on DR.
Item Description:Gesehen am 22.11.2021
Physical Description:Online Resource
ISSN:2212-8778
DOI:10.1016/j.molmet.2021.101333

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