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Evaluation of the inflammatory markers CCL8, CXCL5, and LIF in patients with anastomotic leakage after colorectal cancer surgery

Anastomotic leakage constitutes a dreaded complication after colorectal surgery, leading to increased morbidity and mortality as well as prolonged hospitalization. Most leakages become clinically apparent about 8 days after surgery; however, early detection is quintessential to reduce complications...

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Bibliographic Details
Main Authors: Klupp, Fee (Author) , Schuler, S. (Author) , Kahlert, Christoph (Author) , Halama, Niels (Author) , Franz, Clemens (Author) , Mayer, Philipp (Author) , Schmidt, Thomas (Author) , Ulrich, Alexis (Author)
Format: Article (Journal)
Language:English
Published: 19 April 2020
In: International journal of colorectal disease
Year: 2020, Volume: 35, Issue: 7, Pages: 1221-1230
ISSN:1432-1262
DOI:10.1007/s00384-020-03582-2
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00384-020-03582-2
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Author Notes:F. Klupp, S. Schuler, C. Kahlert, N. Halama, C. Franz, P. Mayer, T. Schmidt, A. Ulrich
Description
Summary:Anastomotic leakage constitutes a dreaded complication after colorectal surgery, leading to increased morbidity and mortality as well as prolonged hospitalization. Most leakages become clinically apparent about 8 days after surgery; however, early detection is quintessential to reduce complications and to improve patients’ outcome. We therefore investigated the significance of specific protein expression profiles as putative biomarkers, indicating anastomotic leakage.
Item Description:Gesehen am 07.12.2021
Physical Description:Online Resource
ISSN:1432-1262
DOI:10.1007/s00384-020-03582-2

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