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Self-extracellular RNA promotes pro-inflammatory response of astrocytes to exogenous and endogenous danger signals

Astrocytes participate in the local innate immune response of the central nervous system. In response to stress such as ischemia, activated cells release endogenous factors known as damage-associated molecular patterns (DAMPs). Self-extracellular RNA (eRNA) is such a ubiquitous alarm signal. However...

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Bibliographic Details
Main Authors: Fischer, Silvia (Author) , Nasyrov, Emil (Author) , Brosien, Monika (Author) , Preissner, Klaus T. (Author) , Marti, Hugo (Author) , Kunze, Reiner (Author)
Format: Article (Journal)
Language:English
Published: 02 November 2021
In: Journal of neuroinflammation
Year: 2021, Volume: 18, Pages: 1-13
ISSN:1742-2094
DOI:10.1186/s12974-021-02286-w
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12974-021-02286-w
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Author Notes:Silvia Fischer, Emil Nasyrov, Monika Brosien, Klaus T. Preissner, Hugo H. Marti and Reiner Kunze

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