Cover Image

GDF-15 protects from macrophage accumulation in a mousemodel of advanced atherosclerosis

The cytokine growth differentiation factor-15 (GDF-15), a member of the TGF beta superfamily, has recently been discovered to play an important role in cardiovascular diseases. It is mostly expressed in macrophages of atherosclerotic lesions, but its impact on advanced atherosclerosis is still unkno...

Full description

Saved in:
Bibliographic Details
Main Authors: Preusch, Michael (Author) , Baeuerle, Matthias (Author) , Albrecht, Claudia (Author) , Blessing, Erwin (Author) , Bischof, Marc (Author) , Katus, Hugo (Author) , Bea, Florian (Author)
Format: Article (Journal)
Language:English
Published: 24 June 2013
In: European journal of medical research
Year: 2013, Volume: 18, Issue: 1, Pages: 1-6
ISSN:2047-783X
DOI:10.1186/2047-783X-18-19
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/2047-783X-18-19
Verlag, lizenzpflichtig, Volltext: https://eurjmedres.biomedcentral.com/articles/10.1186/2047-783X-18-19
Get full text
Author Notes:Michael R. Preusch, Matthias Baeuerle, Claudia Albrecht, Erwin Blessing, Marc Bischof, Hugo A. Katus and Florian Bea
Description
Summary:The cytokine growth differentiation factor-15 (GDF-15), a member of the TGF beta superfamily, has recently been discovered to play an important role in cardiovascular diseases. It is mostly expressed in macrophages of atherosclerotic lesions, but its impact on advanced atherosclerosis is still unknown. This study was performed to evaluate the effects of GDF-15 in an established mouse model of advanced atherosclerosis.
Item Description:Gesehen am 08.12.2021
Physical Description:Online Resource
ISSN:2047-783X
DOI:10.1186/2047-783X-18-19

Similar Items