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Aging is associated with highly defined epigenetic changes in the human epidermis

Altered DNA methylation patterns represent an attractive mechanism for understanding the phenotypic changes associated with human aging. Several studies have described global and complex age-related methylation changes, but their structural and functional significance has remained largely unclear.

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Bibliographic Details
Main Authors: Raddatz, Günter (Author) , Hagemann, Sabine (Author) , Aran, Dvir (Author) , Söhle, Jörn (Author) , Kulkarni, Pranav P. (Author) , Kaderali, Lars (Author) , Hellman, Asaf (Author) , Winnefeld, Marc (Author) , Lyko, Frank (Author)
Format: Article (Journal)
Language:English
Published: 31 October 2013
In: Epigenetics & chromatin
Year: 2013, Volume: 6, Issue: 1, Pages: 1-12
ISSN:1756-8935
DOI:10.1186/1756-8935-6-36
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1756-8935-6-36
Verlag, lizenzpflichtig, Volltext: https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/1756-8935-6-36
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Author Notes:Günter Raddatz, Sabine Hagemann, Dvir Aran, Jörn Söhle, Pranav P. Kulkarni, Lars Kaderali, Asaf Hellman, Marc Winnefeld and Frank Lyko
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Summary:Altered DNA methylation patterns represent an attractive mechanism for understanding the phenotypic changes associated with human aging. Several studies have described global and complex age-related methylation changes, but their structural and functional significance has remained largely unclear.
Item Description:Gesehen am 13.12.2021
Physical Description:Online Resource
ISSN:1756-8935
DOI:10.1186/1756-8935-6-36

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