Limited Plasmodium sporozoite gliding motility in the absence of TRAP family adhesins
Plasmodium sporozoites are the highly motile forms of malaria-causing parasites that are transmitted by the mosquito to the vertebrate host. Sporozoites need to enter and cross several cellular and tissue barriers for which they employ a set of surface proteins. Three of these proteins are members o...
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| Main Authors: | , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
30 October 2021
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| In: |
Malaria journal
Year: 2021, Volume: 20, Pages: 1-12 |
| ISSN: | 1475-2875 |
| DOI: | 10.1186/s12936-021-03960-3 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12936-021-03960-3
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| Author Notes: | Konrad Beyer, Simon Kracht, Jessica Kehrer, Mirko Singer, Dennis Klug and Friedrich Frischknecht |
| Summary: | Plasmodium sporozoites are the highly motile forms of malaria-causing parasites that are transmitted by the mosquito to the vertebrate host. Sporozoites need to enter and cross several cellular and tissue barriers for which they employ a set of surface proteins. Three of these proteins are members of the thrombospondin related anonymous protein (TRAP) family. Here, potential additive, synergistic or antagonistic roles of these adhesion proteins were investigated. |
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| Item Description: | Gesehen am 13.12.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1475-2875 |
| DOI: | 10.1186/s12936-021-03960-3 |