Approaching sites of action of drugs in clinical pharmacology: New analytical options and their challenges

Clinical pharmacology is an important discipline for drug development aiming to define pharmacokinetics (PK), pharmacodynamics (PD) and optimum exposure to drugs, i.e. the concentration-response relationship and its modulators.

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Bibliographic Details
Main Authors: Longuespée, Rémi (Author) , Theile, Dirk (Author) , Fresnais, Margaux (Author) , Burhenne, Jürgen (Author) , Weiß, Johanna (Author) , Haefeli, Walter E. (Author)
Format: Article (Journal)
Language:English
Published: 2021
In: British journal of clinical pharmacology
Year: 2021, Volume: 87, Issue: 3, Pages: 858-874
ISSN:1365-2125
DOI:10.1111/bcp.14543
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1111/bcp.14543
Verlag, kostenfrei, Volltext: https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.14543
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Author Notes:Rémi Longuespée, Dirk Theile, Margaux Fresnais, Jürgen Burhenne, Johanna Weiss, Walter E. Haefeli
Description
Summary:Clinical pharmacology is an important discipline for drug development aiming to define pharmacokinetics (PK), pharmacodynamics (PD) and optimum exposure to drugs, i.e. the concentration-response relationship and its modulators.
Item Description:First published: 02 September 2020
Gesehen am 13.12.2021
Physical Description:Online Resource
ISSN:1365-2125
DOI:10.1111/bcp.14543