XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase
Replication-associated single-ended DNA double-strand breaks (seDSBs) are repaired predominantly through RAD51-mediated homologous recombination (HR). Removal of the non-homologous end-joining (NHEJ) factor Ku from resected seDSB ends is crucial for HR. The coordinated actions of MRE11-CtIP nuclease...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
09 September 2021
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| In: |
Nucleic acids research
Year: 2021, Jahrgang: 49, Heft: 17, Pages: 9906-9925 |
| ISSN: | 1362-4962 |
| DOI: | 10.1093/nar/gkab785 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/nar/gkab785 |
| Verfasserangaben: | Abhishek Bharadwaj Sharma, Hélène Erasimus, Lia Pinto, Marie-Christine Caron, Diyavarshini Gopaul, Thibaut Peterlini, Katrin Neumann, Petr V. Nazarov, Sabrina Fritah, Barbara Klink, Christel C. Herold-Mende, Simone P. Niclou, Philippe Pasero, Patrick Calsou, Jean-Yves Masson, Sébastien Britton, Eric Van Dyck |
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