MiRNA profiling of biliary intraepithelial neoplasia reveals stepwise tumorigenesis in distal cholangiocarcinoma via the miR-451a/ATF2 axis

Distal cholangiocarcinoma (dCCA) is a biliary tract cancer with a dismal prognosis and is often preceded by biliary intraepithelial neoplasia (BilIN), representing the most common biliary non-invasive precursor lesion.

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Main Authors: Löffler, Moritz (Author) , Hu, Jun (Author) , Kirchner, Martina (Author) , Wei, Xiyang (Author) , Xiao, Yi (Author) , Albrecht, Thomas (Author) , Torre, Carolina de la (Author) , Sticht, Carsten (Author) , Banales, Jesus M. (Author) , Vogel, Monika Nadja (Author) , Pathil-Warth, Anita (Author) , Mehrabi, Arianeb (Author) , Hoffmann, Katrin (Author) , Rupp, Christian (Author) , Köhler, Bruno Christian (Author) , Springfeld, Christoph (Author) , Schirmacher, Peter (Author) , Ji, Junfang (Author) , Rössler, Stephanie (Author) , Goeppert, Benjamin (Author)
Format: Article (Journal)
Language:English
Published: 15 September 2020
In: The journal of pathology
Year: 2020, Volume: 252, Issue: 3, Pages: 239-251
ISSN:1096-9896
DOI:10.1002/path.5514
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1002/path.5514
Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/path.5514
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Author Notes:Moritz A. Loeffler, Jun Hu, Martina Kirchner, Xiyang Wei, Yi Xiao, Thomas Albrecht, Carolina De La Torre, Carsten Sticht, Jesus M. Banales, Monika N. Vogel, Anita Pathil-Warth, Arianeb Mehrabi, Katrin Hoffmann, Christian Rupp, Bruno Köhler, Christoph Springfeld, Peter Schirmacher, Junfang Ji, Stephanie Roessler and Benjamin Goeppert
Description
Summary:Distal cholangiocarcinoma (dCCA) is a biliary tract cancer with a dismal prognosis and is often preceded by biliary intraepithelial neoplasia (BilIN), representing the most common biliary non-invasive precursor lesion.
Item Description:Gesehen am 17.12.2021
Physical Description:Online Resource
ISSN:1096-9896
DOI:10.1002/path.5514