The “unnatural” history of colorectal cancer in Lynch syndrome: lessons from colonoscopy surveillance
Individuals with Lynch syndrome (LS), one of the most common inherited cancer syndromes, are at increased risk of developing malignancies, in particular colorectal cancer (CRC). Regular colonoscopy with polypectomy is recommended to reduce CRC risk in LS individuals.
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2021
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| In: |
International journal of cancer
Year: 2021, Volume: 148, Issue: 4, Pages: 800-811 |
| ISSN: | 1097-0215 |
| DOI: | 10.1002/ijc.33224 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1002/ijc.33224 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/ijc.33224 |
| Author Notes: | Aysel Ahadova, Toni T. Seppälä, Christoph Engel, Richard Gallon, John Burn, Elke Holinski-Feder, Verena Steinke-Lange, Gabriela Möslein, Maartje Nielsen, Sanne W. ten Broeke, Luigi Laghi, Mev Dominguez-Valentin, Gabriel Capella, Finlay Macrae, Rodney Scott, Robert Hüneburg, Jacob Nattermann, Michael Hoffmeister, Hermann Brenner, Hendrik Bläker, Magnus von Knebel Doeberitz, Julian R. Sampson, Hans Vasen, Jukka-Pekka Mecklin, Pål Møller, Matthias Kloor |
| Summary: | Individuals with Lynch syndrome (LS), one of the most common inherited cancer syndromes, are at increased risk of developing malignancies, in particular colorectal cancer (CRC). Regular colonoscopy with polypectomy is recommended to reduce CRC risk in LS individuals. |
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| Item Description: | First published: 19 July 2020 Gesehen am 17.12.2021 |
| Physical Description: | Online Resource |
| ISSN: | 1097-0215 |
| DOI: | 10.1002/ijc.33224 |