The “unnatural” history of colorectal cancer in Lynch syndrome: lessons from colonoscopy surveillance

Individuals with Lynch syndrome (LS), one of the most common inherited cancer syndromes, are at increased risk of developing malignancies, in particular colorectal cancer (CRC). Regular colonoscopy with polypectomy is recommended to reduce CRC risk in LS individuals.

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Bibliographic Details
Main Authors: Ahadova, Aysel (Author) , Seppälä, Toni T. (Author) , Engel, Christoph (Author) , Gallon, Richard (Author) , Burn, John (Author) , Holinski-Feder, Elke (Author) , Steinke-Lange, Verena (Author) , Möslein, Gabriela (Author) , Nielsen, Maartje (Author) , Ten Broeke, Sanne W. (Author) , Laghi, Luigi (Author) , Dominguez-Valentin, Mev (Author) , Capella, Gabriel (Author) , Macrae, Finlay (Author) , Scott, Rodney (Author) , Hüneburg, Robert (Author) , Nattermann, Jacob (Author) , Hoffmeister, Michael (Author) , Brenner, Hermann (Author) , Bläker, Hendrik (Author) , Knebel Doeberitz, Magnus von (Author) , Sampson, Julian R. (Author) , Vasen, Hans (Author) , Mecklin, Jukka-Pekka (Author) , Møller, Pål (Author) , Kloor, Matthias (Author)
Format: Article (Journal)
Language:English
Published: 2021
In: International journal of cancer
Year: 2021, Volume: 148, Issue: 4, Pages: 800-811
ISSN:1097-0215
DOI:10.1002/ijc.33224
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1002/ijc.33224
Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/ijc.33224
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Author Notes:Aysel Ahadova, Toni T. Seppälä, Christoph Engel, Richard Gallon, John Burn, Elke Holinski-Feder, Verena Steinke-Lange, Gabriela Möslein, Maartje Nielsen, Sanne W. ten Broeke, Luigi Laghi, Mev Dominguez-Valentin, Gabriel Capella, Finlay Macrae, Rodney Scott, Robert Hüneburg, Jacob Nattermann, Michael Hoffmeister, Hermann Brenner, Hendrik Bläker, Magnus von Knebel Doeberitz, Julian R. Sampson, Hans Vasen, Jukka-Pekka Mecklin, Pål Møller, Matthias Kloor
Description
Summary:Individuals with Lynch syndrome (LS), one of the most common inherited cancer syndromes, are at increased risk of developing malignancies, in particular colorectal cancer (CRC). Regular colonoscopy with polypectomy is recommended to reduce CRC risk in LS individuals.
Item Description:First published: 19 July 2020
Gesehen am 17.12.2021
Physical Description:Online Resource
ISSN:1097-0215
DOI:10.1002/ijc.33224