Somatostatin receptor subtype 2 (sst2) is a potential prognostic marker and a therapeutic target in medulloblastoma

Neuroectodermal tumors in general demonstrate high and dense expression of the somatostatin receptor subtype 2 (sst2). It controls proliferation of both normal and neoplastic cells. sst2 has thus been suggested as a therapeutic target and prognostic marker for certain malignancies.

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Bibliographic Details
Main Authors: Remke, Marc (Author) , Hering, Esther (Author) , Gerber, Nicolas U. (Author) , Kool, Marcel (Author) , Sturm, Dominik (Author) , Rickert, Christian H. (Author) , Gerß, Joachim (Author) , Schulz, Stefan (Author) , Hielscher, Thomas (Author) , Hasselblatt, Martin (Author) , Jeibmann, Astrid (Author) , Hans, Volkmar (Author) , Ramaswamy, Vijay (Author) , Taylor, Michael D. (Author) , Pietsch, Torsten (Author) , Rutkowski, Stefan (Author) , Korshunov, Andrey (Author) , Monoranu, Carmelia-Maria (Author) , Frühwald, Michael C. (Author)
Format: Article (Journal)
Language:English
Published: 16 May 2013
In: Child's nervous system
Year: 2013, Volume: 29, Issue: 8, Pages: 1253-1262
ISSN:1433-0350
DOI:10.1007/s00381-013-2142-4
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00381-013-2142-4
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007%2Fs00381-013-2142-4
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Author Notes:Marc Remke · Esther Hering · Nicolas U. Gerber · Marcel Kool · Dominik Sturm · Christian H. Rickert · Joachim Gerß · Stefan Schulz · Thomas Hielscher · Martin Hasselblatt · Astrid Jeibmann · Volkmar Hans · Vijay Ramaswamy · Michael D. Taylor · Torsten Pietsch · Stefan Rutkowski · Andrey Korshunov · Carmelia-Maria Monoranu · Michael C. Frühwald
Description
Summary:Neuroectodermal tumors in general demonstrate high and dense expression of the somatostatin receptor subtype 2 (sst2). It controls proliferation of both normal and neoplastic cells. sst2 has thus been suggested as a therapeutic target and prognostic marker for certain malignancies.
Item Description:Im Text ist "2" bei "sst2" tiefgestellt
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Physical Description:Online Resource
ISSN:1433-0350
DOI:10.1007/s00381-013-2142-4