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Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays

Multiple myeloma (MM) is characterized by a strong dependence of the tumor cells on their microenvironment, which produces growth factors supporting survival and proliferation of myeloma cells (MMC). In the past few years, many myeloma growth factors (MGF) have been described in the literature. Howe...

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Main Authors: Mahtouk, Karène (Author) , Moreaux, Jérôme (Author) , Hose, Dirk (Author) , Rème, Thierry (Author) , Meißner, Tobias (Author) , Jourdan, Michel (Author) , Rossi, Jean François (Author) , Pals, Steven T. (Author) , Goldschmidt, Hartmut (Author) , Klein, Bernard (Author)
Format: Article (Journal)
Language:English
Published: [2010]
In: BMC cancer
Year: 2010, Volume: 10, Pages: 1-18
ISSN:1471-2407
DOI:10.1186/1471-2407-10-198
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2407-10-198
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Author Notes:Karène Mahtouk, Jérôme Moreaux, Dirk Hose, Thierry Rème, Tobias Meißner, Michel Jourdan, Jean François Rossi, Steven T. Pals, Hartmut Goldschmidt and Bernard Klein
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Summary:Multiple myeloma (MM) is characterized by a strong dependence of the tumor cells on their microenvironment, which produces growth factors supporting survival and proliferation of myeloma cells (MMC). In the past few years, many myeloma growth factors (MGF) have been described in the literature. However, their relative importance and the nature of the cells producing MGF remain unidentified for many of them.
Item Description:Gesehen am 07.01.2022
Physical Description:Online Resource
ISSN:1471-2407
DOI:10.1186/1471-2407-10-198

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