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Atacicept in relapsed/refractory multiple myeloma or active Waldenström's macroglobulinemia: a phase I study

Advanced multiple myeloma (MM) and Waldenström's macroglobulinemia (WM) are incurable B-cell malignancies. This is the first full clinical report of atacicept, a fusion protein that binds to and neutralises the B-cell survival factors, B-lymphocyte stimulator (BLyS) and A proliferation-inducin...

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Main Authors: Rossi, Jean-François (Author) , Moreaux, J. (Author) , Hose, Dirk (Author) , Requirand, G. (Author) , Rose, M. (Author) , Rouillé, V. (Author) , Nestorov, I. (Author) , Mordenti, G. (Author) , Goldschmidt, Hartmut (Author) , Ythier, A. (Author) , Klein, B. (Author)
Format: Article (Journal)
Language:English
Published: 29 September 2009
In: British journal of cancer
Year: 2009, Volume: 101, Issue: 7, Pages: 1051-1058
ISSN:1532-1827
DOI:10.1038/sj.bjc.6605241
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/sj.bjc.6605241
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/6605241
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Author Notes:J.-F. Rossi, J. Moreaux, D. Hose, G. Requirand, M. Rose, V. Rouillé, I. Nestorov, G. Mordenti, H. Goldschmidt, A. Ythier and B. Klein
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Summary:Advanced multiple myeloma (MM) and Waldenström's macroglobulinemia (WM) are incurable B-cell malignancies. This is the first full clinical report of atacicept, a fusion protein that binds to and neutralises the B-cell survival factors, B-lymphocyte stimulator (BLyS) and A proliferation-inducing ligand (APRIL), in MM and WM.
Item Description:Gesehen am 12.01.2022
Physical Description:Online Resource
ISSN:1532-1827
DOI:10.1038/sj.bjc.6605241

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