Clinical evidence for immunomodulation induced by high-dose melphalan and autologous blood stem cell transplantation as cause for complete clinical remission of multiple myeloma-associated cryoglobulin-vasculitis
We present a case report of a patient with cryoglobulin-vasculitis caused by multiple myeloma in Durie/Salmon stage I refractory to conventional therapy modalities treated with high-dose chemotherapy followed by autologous blood stem cell transplantation. While clinical symptoms of vasculitis disapp...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
11 October 2008
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| In: |
International journal of hematology
Year: 2008, Volume: 88, Issue: 4, Pages: 454-456 |
| ISSN: | 1865-3774 |
| DOI: | 10.1007/s12185-008-0177-1 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s12185-008-0177-1
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| Author Notes: | J. Hillengass, A. D. Ho, H. Goldschmidt, R. Waldherr, T. M. Moehler |
| Summary: | We present a case report of a patient with cryoglobulin-vasculitis caused by multiple myeloma in Durie/Salmon stage I refractory to conventional therapy modalities treated with high-dose chemotherapy followed by autologous blood stem cell transplantation. While clinical symptoms of vasculitis disappeared, elevated cryoglobulin levels persisted. Therefore we conclude that the relief of symptoms was caused by an immunomodulation induced by the autologous stem cell transplantation. |
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| Item Description: | Gesehen am 14.01.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1865-3774 |
| DOI: | 10.1007/s12185-008-0177-1 |