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Preclinical investigations towards the first spacer gel application in prostate cancer treatment during particle therapy at HIT

The application of spacer gel represents a promising approach to reliably spare the rectal frontal wall during particle therapy (IJROBP 76:1251-1258, 2010). In order to qualify the spacer gel for the clinical use in particle therapy, a variety of measurements were performed in order to ensure the bi...

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Main Authors: Ruciński, Antoni Wojciech (Author) , Bauer, Julia (Author) , Campbell, Patrick (Author) , Brons, Stephan (Author) , Unholtz, Daniel (Author) , Habl, Gregor (Author) , Herfarth, Klaus (Author) , Debus, Jürgen (Author) , Bert, Christoph (Author) , Parodi, Katia (Author) , Jäkel, Oliver (Author) , Haberer, Thomas (Author)
Format: Article (Journal)
Language:English
Published: 6 June 2013
In: Radiation oncology
Year: 2013, Volume: 8, Issue: 1, Pages: 1-12
ISSN:1748-717X
DOI:10.1186/1748-717X-8-134
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1748-717X-8-134
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Author Notes:Antoni Ruciński, Julia Bauer, Patrick Campbell, Stephan Brons, Daniel Unholtz, Gregor Habl, Klaus Herfarth, Jürgen Debus, Christoph Bert, Katia Parodi, Oliver Jäkel and Thomas Haberer
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Summary:The application of spacer gel represents a promising approach to reliably spare the rectal frontal wall during particle therapy (IJROBP 76:1251-1258, 2010). In order to qualify the spacer gel for the clinical use in particle therapy, a variety of measurements were performed in order to ensure the biological compatibility of the gel, its physical stability during and after the irradiation, and a proper definition of the gel in terms of the Hounsfield Unit (HU) values for the treatment planning system. The potential for the use of the spacer gel for particle therapy monitoring with off-line Positron Emission Tomography (PET) was also investigated.
Item Description:Gesehen am 21.01.2022
Physical Description:Online Resource
ISSN:1748-717X
DOI:10.1186/1748-717X-8-134

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