Low-dose gemcitabine depletes regulatory T cells and improves survival in the orthotopic Panc02 model of pancreatic cancer

What's new? Regulatory T cells (Treg) appear to contribute to poor prognosis in patients with pancreatic ductal adenocarcinoma (PDAC), suggesting that Treg cells are key therapeutic targets.

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Bibliographic Details
Main Authors: Shevchenko, Ivan (Author) , Karakhanova, Svetlana (Author) , Soltek, Sabine (Author) , Link, Julia (Author) , Bayry, Jagadeesh (Author) , Werner, Jens (Author) , Umansky, Viktor (Author) , Bazhin, Alexandr V. (Author)
Format: Article (Journal)
Language:English
Published: 2013
In: International journal of cancer
Year: 2013, Volume: 133, Issue: 1, Pages: 98-107
ISSN:1097-0215
DOI:10.1002/ijc.27990
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1002/ijc.27990
Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/ijc.27990
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Author Notes:Ivan Shevchenko, Svetlana Karakhanova, Sabine Soltek, Julia Link, Jagadeesh Bayry, Jens Werner, Viktor Umansky and Alexandr V. Bazhin
Description
Summary:What's new? Regulatory T cells (Treg) appear to contribute to poor prognosis in patients with pancreatic ductal adenocarcinoma (PDAC), suggesting that Treg cells are key therapeutic targets.
Item Description:First published: 12 December 2012
Gesehen am 26.01.2022
Physical Description:Online Resource
ISSN:1097-0215
DOI:10.1002/ijc.27990