Effectiveness and cost-effectiveness of four different strategies for SARS-CoV-2 surveillance in the general population (CoV-Surv Study): study protocol for a two-factorial randomized controlled multi-arm trial with cluster sampling

To achieve higher effectiveness in population-based SARS-CoV-2 surveillance and to reliably predict the course of an outbreak, screening, and monitoring of infected individuals without major symptoms (about 40% of the population) will be necessary. While current testing capacities are also used to i...

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Main Authors: Deckert, Andreas (Author) , Anders, Simon (Author) , De Allegri, Manuela (Author) , Nguyen, Hoa Thi (Author) , Souares-Coutant, Aurélia (Author) , McMahon-Rössle, Shannon A. (Author) , Meurer, Matthias (Author) , Burk, Robin (Author) , Sand, Matthias (Author) , Köppel, Lisa (Author) , Maier-Hein, Lena (Author) , Roß, Tobias (Author) , Adler, Tim (Author) , Siems, Tobias (Author) , Brugnara Kirchmann, Lúcia (Author) , Brenner, Stephan (Author) , Herbst, Konrad (Author) , Kirrmaier, Daniel (Author) , Duan, Yuanqiang (Author) , Ovchinnikova, Svetlana (Author) , Börner, Kathleen (Author) , Marx, Michael (Author) , Kräusslich, Hans-Georg (Author) , Knop, Michael (Author) , Bärnighausen, Till (Author) , Denkinger, Claudia M. (Author)
Format: Article (Journal)
Language:English
Published: 26 September 2021
In: Trials
Year: 2021, Volume: 22, Pages: 1-9
ISSN:1468-6694
DOI:10.1186/s13063-021-05619-5
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13063-021-05619-5
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Author Notes:Andreas Deckert, Simon Anders, Manuela De Allegri, Hoa Thi Nguyen, Aurélia Souares, Shannon McMahon, Matthias Meurer, Robin Burk, Matthias Sand, Lisa Koeppel, Lena Maier Hein, Tobias Roß, Tim Adler, Tobias Siems, Lucia Brugnara, Stephan Brenner, Konrad Herbst, Daniel Kirrmaier, Yuanqiang Duan, Svetlana Ovchinnikova, Kathleen Boerner, Michael Marx, Hans-Georg Kräusslich, Michael Knop, Till Bärnighausen, Claudia Denkinger
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Summary:To achieve higher effectiveness in population-based SARS-CoV-2 surveillance and to reliably predict the course of an outbreak, screening, and monitoring of infected individuals without major symptoms (about 40% of the population) will be necessary. While current testing capacities are also used to identify such asymptomatic cases, this rather passive approach is not suitable in generating reliable population-based estimates of the prevalence of asymptomatic carriers to allow any dependable predictions on the course of the pandemic.
Item Description:Gesehen am 01.02.2022
Physical Description:Online Resource
ISSN:1468-6694
DOI:10.1186/s13063-021-05619-5