Buchumschlag

Domino decarboxylative arylation and c-o selective bond formation toward chromeno(2,3-b)pyridine-2-one skeletons

Practical Pd-catalyzed 2-pyridones were designed to achieve chromeno(2,3-b)pyridine-2-ones. The reaction proceeds through domino nucleophilic addition and decarboxylative arylation, respectively. This methodology offers a moderately efficient approach to construct the bioactive, fused-heterocyclic s...

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Hauptverfasser: Ahadi, Elmira Meghrazi (VerfasserIn) , Abbasi Kejani, Alireza (VerfasserIn) , Khosravi, Hormoz (VerfasserIn) , Fathi Vavsari, Vaezeh (VerfasserIn) , Balalaie, Saeed (VerfasserIn) , Rominger, Frank (VerfasserIn) , Bijanzadeh, Hamid Reza (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: September 8, 2021
In: The journal of organic chemistry
Year: 2021, Jahrgang: 86, Heft: 18, Pages: 12705-12713
ISSN:1520-6904
DOI:10.1021/acs.joc.1c01220
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1021/acs.joc.1c01220
Volltext
Verfasserangaben:Elmira Meghrazi Ahadi, Alireza Abbasi Kejani, Hormoz Khosravi, Vaezeh Fathi Vavsari, Saeed Balalaie, Frank Rominger, and Hamid Reza Bijanzadeh
Beschreibung
Zusammenfassung:Practical Pd-catalyzed 2-pyridones were designed to achieve chromeno(2,3-b)pyridine-2-ones. The reaction proceeds through domino nucleophilic addition and decarboxylative arylation, respectively. This methodology offers a moderately efficient approach to construct the bioactive, fused-heterocyclic skeletons via selective C-O bond formation and decarboxylative arylation in a single step with high selectivity and good yields.
Beschreibung:Gesehen am 01.02.2022
Beschreibung:Online Resource
ISSN:1520-6904
DOI:10.1021/acs.joc.1c01220

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