Triple channel analysis of Gafchromic EBT3 irradiated with clinical carbon-ion beams
Self-developing radiochromic film is widely used in radiotherapy QA procedures. To compensate for typical film inhomogeneities, the triple channel analysis method is commonly used for photon-irradiated film. We investigated the applicability of this method for GafchromicTMEBT3 (Ashland) film irradia...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
July 2021
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| In: |
Physica medica
Year: 2021, Volume: 87, Pages: 123-130 |
| ISSN: | 1724-191X |
| DOI: | 10.1016/j.ejmp.2021.06.009 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ejmp.2021.06.009 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1120179721002295 
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| Author Notes: | Kim Marina Holm, Eduardo G. Yukihara, Md Foiez Ahmed, Steffen Greilich, Oliver Jäkel |
| Summary: | Self-developing radiochromic film is widely used in radiotherapy QA procedures. To compensate for typical film inhomogeneities, the triple channel analysis method is commonly used for photon-irradiated film. We investigated the applicability of this method for GafchromicTMEBT3 (Ashland) film irradiated with a clinically used carbon-ion beam. Calibration curves were taken from EBT3 film specimens irradiated with monoenergetic carbon-ion beams of different doses. Measurements of the lateral field shape and homogeneity were performed in the middle of a passively modulated spread-out Bragg peak and compared to simultaneous characterization by means of a 2D ionization chamber array. Additional measurements to investigate the applicability of EBT3 for quality assurance (QA) measurement in carbon-ion beams were performed. The triple-channel analysis reduced the relative standard deviation of the doses in a uniform carbon ion field by 30% (from 1.9% to 1.3%) and reduced the maximum deviation by almost a factor of 3 (from 28.6% to 9.8%), demonstrating the elimination of film artifacts. The corrected film signal showed considerably improved image quality and quantitative agreement with the ionization chamber data, thus providing a clear rationale for the usage of the triple channel analysis in carbon-beam QA. |
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| Item Description: | Available online 16 June 2021, version of record 16 June 2021 |
| Physical Description: | Online Resource |
| ISSN: | 1724-191X |
| DOI: | 10.1016/j.ejmp.2021.06.009 |