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Genome-wide CRISPR screen identifies RACK1 as a critical host factor for flavivirus replication

Cellular factors are critical in all facets of viral lifecycles, where overlapping - interactions between the virus and host can be exploited as possible avenues for the - development of antiviral therapeutics. Using a genome-wide CRISPR knockout screening - ...

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Bibliographic Details
Main Authors: Shue, Byron (Author) , Chiramel, Abhilash I. (Author) , Cerikan, Berati (Author) , To, Thu-Hien (Author) , Frölich, Sonja (Author) , Pederson, Stephen M. (Author) , Kirby, Emily N. (Author) , Eyre, Nicholas S. (Author) , Bartenschlager, Ralf (Author) , Best, Sonja M. (Author) , Beard, Michael R. (Author)
Format: Article (Journal)
Language:English
Published: 29 September 2021
In: Journal of virology
Year: 2021, Volume: 95, Issue: 24, Pages: 1-18
ISSN:1098-5514
DOI:10.1128/JVI.00596-21
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1128/JVI.00596-21
Verlag, lizenzpflichtig, Volltext: https://journals.asm.org/doi/abs/10.1128/JVI.00596-21
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Author Notes:Byron Shue, Abhilash I. Chiramel, Berati Cerikan, Thu-Hien To, Sonja Frölich, Stephen M. Pederson, Emily N. Kirby, Nicholas S. Eyre, Ralf F. W. Bartenschlager, Sonja M. Best, Michael R. Beard
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Summary:Cellular factors are critical in all facets of viral lifecycles, where overlapping - interactions between the virus and host can be exploited as possible avenues for the - development of antiviral therapeutics. Using a genome-wide CRISPR knockout screening - ...
Item Description:Gesehen am 02.03.2022
Physical Description:Online Resource
ISSN:1098-5514
DOI:10.1128/JVI.00596-21

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