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How can we consider variable RBE and LETd prediction during clinical practice?: A pediatric case report at the Normandy Proton Therapy Centre using an independent dose engine

To develop an auxiliary GPU-accelerated proton therapy (PT) dose and LETd engine for the IBA Proteus®ONE PT system. A pediatric low-grade glioma case study is reported using FRoG during clinical practice, highlighting potential treatment planning insights using variable RBE dose (DvRBE) and LETd as...

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Main Authors: Mein, Stewart (Author) , Kopp, Benedikt (Author) , Vela, Anthony (Author) , Dutheil, Pauline (Author) , Lesueur, Paul (Author) , Stefan, Dinu (Author) , Debus, Jürgen (Author) , Haberer, Thomas (Author) , Abdollahi, Amir (Author) , Mairani, Andrea (Author) , Tessonnier, Thomas (Author)
Format: Article (Journal)
Language:English
Published: 04 February 2022
In: Radiation oncology
Year: 2022, Volume: 17, Pages: 1-16
ISSN:1748-717X
DOI:10.1186/s13014-021-01960-w
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13014-021-01960-w
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Author Notes:Stewart Mein, Benedikt Kopp, Anthony Vela, Pauline Dutheil, Paul Lesueur, Dinu Stefan, Jürgen Debus, Thomas Haberer, Amir Abdollahi, Andrea Mairani andThomas Tessonnier
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Summary:To develop an auxiliary GPU-accelerated proton therapy (PT) dose and LETd engine for the IBA Proteus®ONE PT system. A pediatric low-grade glioma case study is reported using FRoG during clinical practice, highlighting potential treatment planning insights using variable RBE dose (DvRBE) and LETd as indicators for clinical decision making in PT.
Item Description:Im Titel ist "d" nach "LET" tiefgestellt
Gesehen am 09.03.2022
Physical Description:Online Resource
ISSN:1748-717X
DOI:10.1186/s13014-021-01960-w

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