How can we consider variable RBE and LETd prediction during clinical practice?: A pediatric case report at the Normandy Proton Therapy Centre using an independent dose engine
To develop an auxiliary GPU-accelerated proton therapy (PT) dose and LETd engine for the IBA Proteus®ONE PT system. A pediatric low-grade glioma case study is reported using FRoG during clinical practice, highlighting potential treatment planning insights using variable RBE dose (DvRBE) and LETd as...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
04 February 2022
|
| In: |
Radiation oncology
Year: 2022, Jahrgang: 17, Pages: 1-16 |
| ISSN: | 1748-717X |
| DOI: | 10.1186/s13014-021-01960-w |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13014-021-01960-w |
| Verfasserangaben: | Stewart Mein, Benedikt Kopp, Anthony Vela, Pauline Dutheil, Paul Lesueur, Dinu Stefan, Jürgen Debus, Thomas Haberer, Amir Abdollahi, Andrea Mairani andThomas Tessonnier |
| Zusammenfassung: | To develop an auxiliary GPU-accelerated proton therapy (PT) dose and LETd engine for the IBA Proteus®ONE PT system. A pediatric low-grade glioma case study is reported using FRoG during clinical practice, highlighting potential treatment planning insights using variable RBE dose (DvRBE) and LETd as indicators for clinical decision making in PT. |
|---|---|
| Beschreibung: | Im Titel ist "d" nach "LET" tiefgestellt Gesehen am 09.03.2022 |
| Beschreibung: | Online Resource |
| ISSN: | 1748-717X |
| DOI: | 10.1186/s13014-021-01960-w |