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Extrapulmonary sarcoidosis of liver and pancreas: a case report and review of literature

Sarcoidosis is a chronic multisystemic granulomatous disease of unknown origin, which can involve nearly all organs. In the case of an infrequent gastrointestinal tract involvement in systemic sarcoidosis, granulomas of the liver are most commonly described while isolated pancreatic sarcoid lesions...

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Main Authors: Harder, Hermann (Author) , Büchler, Markus W. (Author) , Fröhlich, Boris Erwin (Author) , Ströbel, Philipp (Author) , Bergmann, Frank (Author) , Neff, Wolfgang (Author) , Singer, Manfred V. (Author)
Format: Article (Journal)
Language:English
Published: 2007 May 7
In: World journal of gastroenterology
Year: 2007, Volume: 13, Issue: 17, Pages: 2504-2509
ISSN:2219-2840
DOI:10.3748/wjg.v13.i17.2504
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3748/wjg.v13.i17.2504
Verlag, lizenzpflichtig, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146771/
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Author Notes:Hermann Harder, Markus W Büchler, Boris Fröhlich, Philipp Ströbel, Frank Bergmann, Wolfgang Neff, Manfred V Singer
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Summary:Sarcoidosis is a chronic multisystemic granulomatous disease of unknown origin, which can involve nearly all organs. In the case of an infrequent gastrointestinal tract involvement in systemic sarcoidosis, granulomas of the liver are most commonly described while isolated pancreatic sarcoid lesions are rarely seen. We report a case of systemic sarcoidosis with exclusive extrapulmonal involvement of the liver and the pancreas in a 71-year-old white man. The diagnosis of liver involvement was confirmed by biopsy. Pancreatic surgery was needed because preoperative evaluation could not exclude pancreatic cancer and for biliary decompression. An extensive literature review of systemic sarcoidosis, focusing on reported cases with unusual presentation of sarcoidosis in the liver and the pancreas, its diagnosis, treatment, and prognosis was made.
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Physical Description:Online Resource
ISSN:2219-2840
DOI:10.3748/wjg.v13.i17.2504

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