Nature and nurture in vitamin B12 deficiency
We report on a child in whom severe nutritional vitamin B12 deficiency was exacerbated by a genetic impairment of the folate cycle, causing reduced CSF concentrations of the methyl group donor 5-methyltetrahydrofolate. Some patients with vitamin B12 deficiency may benefit from high dose folic acid s...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
July 01, 2002
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| In: |
Archives of disease in childhood
Year: 2002, Volume: 87, Issue: 1, Pages: 75-76 |
| ISSN: | 1468-2044 |
| DOI: | 10.1136/adc.87.1.75 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1136/adc.87.1.75 Verlag, lizenzpflichtig, Volltext: https://adc.bmj.com/content/87/1/75 
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| Author Notes: | J. Zschocke, S. Schindler, G.F. Hoffmann, M. Albani |
| Summary: | We report on a child in whom severe nutritional vitamin B12 deficiency was exacerbated by a genetic impairment of the folate cycle, causing reduced CSF concentrations of the methyl group donor 5-methyltetrahydrofolate. Some patients with vitamin B12 deficiency may benefit from high dose folic acid supplementation, even if plasma concentrations are high. |
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| Item Description: | Gesehen am 31.03.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1468-2044 |
| DOI: | 10.1136/adc.87.1.75 |