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Development of methodology for assessing steroid-tapering in clinical trials for biologics in asthma

Long-term use of oral corticosteroids (OCS) is associated with a risk of adverse events and comorbidities. As such, a goal in assessing the efficacy of biologics in severe asthma is often to monitor reduction in OCS usage. Importantly, however, OCS dose reductions must be conducted without loss of d...

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Bibliographic Details
Main Authors: Korn, Stephanie (Author) , Howarth, Peter (Author) , Smith, Steven G. (Author) , Price, Robert G. (Author) , Yancey, Steven W. (Author) , Prazma, Charlene M. (Author) , Bel, Elisabeth H. (Author)
Format: Article (Journal)
Language:English
Published: 04 March 2022
In: Respiratory research
Year: 2022, Volume: 23, Pages: 1-9
ISSN:1465-993X
DOI:10.1186/s12931-022-01959-1
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12931-022-01959-1
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Author Notes:Stephanie Korn, Peter Howarth, Steven G. Smith, Robert G. Price, Steven W. Yancey, Charlene M. Prazma and Elisabeth H. Bel
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Summary:Long-term use of oral corticosteroids (OCS) is associated with a risk of adverse events and comorbidities. As such, a goal in assessing the efficacy of biologics in severe asthma is often to monitor reduction in OCS usage. Importantly, however, OCS dose reductions must be conducted without loss of disease control.
Item Description:Gesehen am 05.04.2022
Physical Description:Online Resource
ISSN:1465-993X
DOI:10.1186/s12931-022-01959-1

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