Incidental findings in whole-body MR imaging of a population-based cohort study: Frequency, management and psychosocial consequences
Objectives - Management of incidental findings (IF) remains controversial but highly relevant. Our aim was to assess the frequency, management and psychosocial consequences of IF reporting in a population-based cohort study undergoing whole-body MR imaging. - Methods - The study was nested in a pros...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2021
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| In: |
European journal of radiology
Year: 2021, Volume: 134, Pages: 1-6 |
| ISSN: | 1872-7727 |
| DOI: | 10.1016/j.ejrad.2020.109451 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ejrad.2020.109451 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0720048X20306410 
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| Author Notes: | Christopher L. Schlett, Susanne Rospleszcz, Dorina Korbmacher, Roberto Lorbeer, Sigrid Auweter, Holger Hetterich, Sonja Selder, Margit Heier, Birgit Linkohr, Sabine Weckbach, Birgit Ertl-Wagner, Annette Peters, Fabian Bamberg |
| Summary: | Objectives - Management of incidental findings (IF) remains controversial but highly relevant. Our aim was to assess the frequency, management and psychosocial consequences of IF reporting in a population-based cohort study undergoing whole-body MR imaging. - Methods - The study was nested in a prospective cohort from a longitudinal, population-based cohort (KORA-FF4) in southern Germany. All MR obtained on 3T MR scanner were reviewed by board-certified radiologists regarding clinically relevant IF. A baseline and follow-up questionnaires including PHQ-9 were completed prior to and 6-month after to the scan. - Results - Of 400 participants (56.3±9.2years, 58 % male) undergoing whole-body MR, IF were found in 22 % of participants (n=89); most frequently located in the abdominal sequences. In the pre-scan survey, most participants stated as the motivation that they wanted to “contribute to a scientific purpose” (91 %), while “knowing whether I’m healthy” was the most frequent motivation reported 6 months post-scan (88 %). The desire for IF reporting increased over time (pre- vs. 6-months-post-scan), also for clinically less important IF (72 % vs. 84 %, p=0.001). Regarding psychosocial impact, a small portion (3.4 %) reported that awaiting the IF report added “definitely” or “very probably” additional stress burden. Of participants with reported IF, 56.8 % classified the results as “very helpful”. In the post-scan survey moderate depression was observed in 3.3 % and severe depression in 1.2 %. This did not differ between participants with and without reported IF. - Conclusion - In a cohort with whole-body MR imaging, the prevalence of IF was high. Participants considered reporting of IF highly important and added only minor psychological burden. |
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| Item Description: | Online Publikationsdatum: 28 November 2020 Gesehen am 23.04.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1872-7727 |
| DOI: | 10.1016/j.ejrad.2020.109451 |