Incidental findings in whole-body MR imaging of a population-based cohort study: Frequency, management and psychosocial consequences

Objectives - Management of incidental findings (IF) remains controversial but highly relevant. Our aim was to assess the frequency, management and psychosocial consequences of IF reporting in a population-based cohort study undergoing whole-body MR imaging. - Methods - The study was nested in a pros...

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Hauptverfasser: Schlett, Christopher L. (VerfasserIn) , Rospleszcz, Susanne (VerfasserIn) , Korbmacher, Dorina (VerfasserIn) , Lorbeer, Roberto (VerfasserIn) , Auweter, Sigrid (VerfasserIn) , Hetterich, Holger (VerfasserIn) , Selder, Sonja (VerfasserIn) , Heier, Margit (VerfasserIn) , Linkohr, Birgit (VerfasserIn) , Weckbach, Sabine (VerfasserIn) , Ertl-Wagner, Birgit (VerfasserIn) , Peters, Annette (VerfasserIn) , Bamberg, Fabian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2021
In: European journal of radiology
Year: 2021, Jahrgang: 134, Pages: 1-6
ISSN:1872-7727
DOI:10.1016/j.ejrad.2020.109451
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ejrad.2020.109451
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0720048X20306410
Volltext
Verfasserangaben:Christopher L. Schlett, Susanne Rospleszcz, Dorina Korbmacher, Roberto Lorbeer, Sigrid Auweter, Holger Hetterich, Sonja Selder, Margit Heier, Birgit Linkohr, Sabine Weckbach, Birgit Ertl-Wagner, Annette Peters, Fabian Bamberg

MARC

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520 |a Objectives - Management of incidental findings (IF) remains controversial but highly relevant. Our aim was to assess the frequency, management and psychosocial consequences of IF reporting in a population-based cohort study undergoing whole-body MR imaging. - Methods - The study was nested in a prospective cohort from a longitudinal, population-based cohort (KORA-FF4) in southern Germany. All MR obtained on 3T MR scanner were reviewed by board-certified radiologists regarding clinically relevant IF. A baseline and follow-up questionnaires including PHQ-9 were completed prior to and 6-month after to the scan. - Results - Of 400 participants (56.3±9.2years, 58 % male) undergoing whole-body MR, IF were found in 22 % of participants (n=89); most frequently located in the abdominal sequences. In the pre-scan survey, most participants stated as the motivation that they wanted to “contribute to a scientific purpose” (91 %), while “knowing whether I’m healthy” was the most frequent motivation reported 6 months post-scan (88 %). The desire for IF reporting increased over time (pre- vs. 6-months-post-scan), also for clinically less important IF (72 % vs. 84 %, p=0.001). Regarding psychosocial impact, a small portion (3.4 %) reported that awaiting the IF report added “definitely” or “very probably” additional stress burden. Of participants with reported IF, 56.8 % classified the results as “very helpful”. In the post-scan survey moderate depression was observed in 3.3 % and severe depression in 1.2 %. This did not differ between participants with and without reported IF. - Conclusion - In a cohort with whole-body MR imaging, the prevalence of IF was high. Participants considered reporting of IF highly important and added only minor psychological burden. 
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