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PARP inhibition in atherosclerosis and its effects on dendritic cells, T cells and auto-antibody levels

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Atherosclerosis is a chronic inflammatory process. Poly(ADP-ribose) polymerase-1 (PARP), a nuclear enzyme linked to DNA repair, has been shown to be involved in atherogenesis; however, the effects on dendritic cells, T cells and serum auto-antibody levels are not fully understood.

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Bibliographic Details
Main Authors: Erbel, Christian (Author) , Achenbach, Jessica (Author) , Akhavanpoor, Mohammadreza (Author) , Dengler, TJ (Author) , Lasitschka, Felix (Author) , Gleißner, Christian A. (Author) , Bea, F. (Author) , Katus, Hugo (Author) , Szabó, Gábor (Author)
Format: Article (Journal)
Language:English
Published: 08 August 2011
In: European journal of medical research
Year: 2011, Volume: 16, Issue: 8, Pages: 367-374
ISSN:2047-783X
DOI:10.1186/2047-783X-16-8-367
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/2047-783X-16-8-367
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Author Notes:C. Erbel, J. Achenbach, M. Akhavanpoor, T.J. Dengler, F. Lasitschka, C.A. Gleissner, F. Bea, H.A. Katus, G. Szabo
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Summary:Atherosclerosis is a chronic inflammatory process. Poly(ADP-ribose) polymerase-1 (PARP), a nuclear enzyme linked to DNA repair, has been shown to be involved in atherogenesis; however, the effects on dendritic cells, T cells and serum auto-antibody levels are not fully understood.
Item Description:Gesehen am 29.04.2022
Physical Description:Online Resource
ISSN:2047-783X
DOI:10.1186/2047-783X-16-8-367

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