Balloon valvuloplasty in the treatment of congenital aortic valve stenosis - a retrospective multicenter survey of more than 1000 patients
Background - The value of balloon valvuloplasty of the aortic valve in childhood is still under debate. - Objective - To evaluate the results of the procedure in a retrospective multicenter survey of a large cohort over a long time interval. - Methods - Retrospective analysis of 1004 patients with b...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2011
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| In: |
International journal of cardiology
Year: 2011, Jahrgang: 149, Heft: 2, Pages: 182-185 |
| ISSN: | 1874-1754 |
| DOI: | 10.1016/j.ijcard.2010.01.005 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ijcard.2010.01.005 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0167527310000252 
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| Verfasserangaben: | P. Ewert, H. Bertram, J. Breuer, I. Dähnert, S. Dittrich, A. Eicken, M. Emmel, G. Fischer, R. Gitter, M. Gorenflo, N. Haas, E. Kitzmüller, A. Koch, O. Kretschmar, A. Lindinger, I. Michel-Behnke, J.H. Nuernberg, M. Peuster, K. Walter, P. Zartner, F. Uhlemann |
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| 245 | 1 | 0 | |a Balloon valvuloplasty in the treatment of congenital aortic valve stenosis - a retrospective multicenter survey of more than 1000 patients |c P. Ewert, H. Bertram, J. Breuer, I. Dähnert, S. Dittrich, A. Eicken, M. Emmel, G. Fischer, R. Gitter, M. Gorenflo, N. Haas, E. Kitzmüller, A. Koch, O. Kretschmar, A. Lindinger, I. Michel-Behnke, J.H. Nuernberg, M. Peuster, K. Walter, P. Zartner, F. Uhlemann |
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| 520 | |a Background - The value of balloon valvuloplasty of the aortic valve in childhood is still under debate. - Objective - To evaluate the results of the procedure in a retrospective multicenter survey of a large cohort over a long time interval. - Methods - Retrospective analysis of 1004 patients with balloon valvuloplasty of the aortic valve performed between 9/1985 and 10/2006 at 20 centers in Germany, Austria and Switzerland. Amongst others, the following parameters were evaluated before and after the procedure as well as at the end of follow-up or before surgery: clinical status, left ventricular function, transaortic pressure gradient, degree of aortic regurgitation, freedom from re-intervention or surgery. - Patients - Patients from 1day to 18years of age with aortic valve stenosis were divided into four groups: 334 newborns (1-28days); 249 infants (29-365days); 211 children (1-10years), and 210 adolescents (10-18years). - Results - Median follow-up was 32months (0days to 17.5years). After dilatation the pressure gradient decreased from 65 (±24)mm Hg to 26 (±16)mm Hg and remained stable during follow-up. The newborns were the most affected patients. Approximately 60% of them had clinical symptoms and impaired left ventricular function before intervention. Complication rate was 15% in newborns, 11% in infants and 6% in older children. Independently of age, 50% of all patients were free from surgery 10years after intervention. - Conclusions - In this retrospective multicenter study, balloon valvuloplasty of the aortic valve has effectively postponed the need for surgery in infants, children and adolescents up to 18years of age. | ||
| 650 | 4 | |a Aortic valve | |
| 650 | 4 | |a Balloon valvuloplasty | |
| 650 | 4 | |a Transcatheter therapy | |
| 700 | 1 | |a Bertram, H. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Breuer, J. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Dähnert, I. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Dittrich, S. |e VerfasserIn |4 aut | |
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| 700 | 1 | |a Koch, A. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kretschmar, O. |e VerfasserIn |4 aut | |
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| 700 | 1 | |a Walter, K. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Zartner, P. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Uhlemann, F. |e VerfasserIn |4 aut | |
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