Poorly differentiated small cell carcinoma of the pancreas: a case report and review of the literature
Small cell carcinoma (SCC) of the pancreas is a rare malignancy with an extremely poor prognosis. We present the case of a 74-year-old man with a 2-month history of upper abdominal discomfort who was diagnosed with SCC of the pancreas tail, involvement of peri-pancreatic and mesenteric lymph nodes a...
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| Main Authors: | , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
August 27, 2004
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| In: |
Pancreatology
Year: 2004, Volume: 4, Issue: 6, Pages: 521-526 |
| ISSN: | 1424-3911 |
| DOI: | 10.1159/000080526 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000080526 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1424390304800383 
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| Author Notes: | Simone Berkel, Frank Hummel, Jochen Gaa, Walter Back, Ralf Hofheinz, Wolfgang Queisser, Manfred V. Singer, Matthias Löhr |
| Summary: | Small cell carcinoma (SCC) of the pancreas is a rare malignancy with an extremely poor prognosis. We present the case of a 74-year-old man with a 2-month history of upper abdominal discomfort who was diagnosed with SCC of the pancreas tail, involvement of peri-pancreatic and mesenteric lymph nodes and multiple liver metastases (extended disease). A CT scan and a positive somatostatin receptor scintigraphy showed no evidence of a primary lung tumour. The diagnosis of a SCC was confirmed by biopsy. Local tumour control could be achieved by gemcitabine once a week and a long-acting somatostatin analogue once a month, but liver metastasis showed progress. Thus, 5-fluorouracil on a weekly basis was started. The patient died 8 months after diagnosis and had not been hospitalised in the meantime. |
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| Item Description: | Gesehen am 03.05.2022 |
| Physical Description: | Online Resource |
| ISSN: | 1424-3911 |
| DOI: | 10.1159/000080526 |